Sexual infantilism: Difference between revisions
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{{mergeto|Delayed puberty|date=June 2008}} |
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'''Sexual infantilism''' or '''genital infantilism''' is the syndrome of delayed or arrested development of [[sexual organ]]s i.e. |
'''Sexual infantilism''' or '''genital infantilism''' is the syndrome of delayed or arrested development of [[sexual organ]]s, i.e. [[delayed puberty]] for a number of [[congenital disorder|congenital]] and [[endocrine disorder|endocrine]] [[disorder]]s.<ref name=gg>Francis S. Greenspan, David G. Gardner (2004) Basic & Clinical Endocrinology, ISBN 0071402977, Chapter 15 "Puberty, Section "Delayed Puberty or Absent Puberty" (Sexual Infantilism)", pp. 617-627.</ref> |
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Examples of disorders that exhibit sexual infantilism are the [[Turner syndrome]] and various forms of [[congenital adrenal hyperplasia]].<ref name=gg/> |
Examples of disorders that exhibit sexual infantilism are the [[Turner syndrome]] and various forms of [[congenital adrenal hyperplasia]].<ref name=gg/> |
Revision as of 05:56, 21 February 2009
![]() | It has been suggested that this article be merged into Delayed puberty. (Discuss) Proposed since June 2008. |
Sexual infantilism or genital infantilism is the syndrome of delayed or arrested development of sexual organs, i.e. delayed puberty for a number of congenital and endocrine disorders.[1]
Examples of disorders that exhibit sexual infantilism are the Turner syndrome and various forms of congenital adrenal hyperplasia.[1]
Sexual infantilism in boys
Genital infantilism may be be indicative of gonadotropin deficiency resulting from a number of congenital and acquired abnormalities of the central nervous system. Congenital sources of gonadotropin deficiency are described for Kallmann syndrome,congenital adrenal hyperplasia, Prader-Willi syndrome, and Biedl-Bardet syndrome. Acquired abnormalities include some brain tumors (e.g., craniopharyngioma, prolactinoma, germinoma, glioma), diseases of hypothalamus, irradiation and trauma. Pubertal delay due to gonadotropin deficiency is treated with testosterone replacement or with HCG [2]
Abhormal pubertal progressing may be observed for testicular failure, associated with low testosterone levels and high gonadotropin levels, with most common cause being the Klinefelter syndrome. Other possible causes of testicular failure are mumps orchitis, Coxsackievirus B, irradiation, chemotherapy, and trauma. Testicular failure is treated with testosterone replacement.[2]
Sexual infantilism in girls
Observed for gonadotropin deficiency, as in boys and with primary ovarian failure. [2]
See also
- Hypogonadism, lack of function of the gonads (ovaries or testes).
References
- ^ a b Francis S. Greenspan, David G. Gardner (2004) Basic & Clinical Endocrinology, ISBN 0071402977, Chapter 15 "Puberty, Section "Delayed Puberty or Absent Puberty" (Sexual Infantilism)", pp. 617-627.
- ^ a b c Marianne J. Legato, ed. (2004) "Principles of Gender-Specific Medicine, Volume 1-2", ISBN 0124409059, p. 22