Cord Blood Registry: Difference between revisions
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{{Infobox company |
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{{linkrot|date=March 2014}} |
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| name = Cord Blood Registry |
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{{Advert|date=March 2014}} |
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| logo = [[File:Cord Blood Registry Logo.png|150px]] |
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| type = Private |
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| foundation = 1992 |
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| founder = Tom Moore and Wendy Grant |
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| location_city = San Bruno, California 94066 |
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| location_country = United States |
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| key_people = Geoff Crouse, President & CEO |
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| services = Cord blood stem cells preservation and research |
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| homepage = [http://www.cordblood.com/ www.cordblood.com] |
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}}'''Cord Blood Registry''' is a biotechnology company headquartered in [[San Bruno, California]], founded in 1992 by father and daughter Tom Moore and Wendy Grant.<ref>{{cite web|title=Smart Science. Healthy Families.|url=http://www.cordblood.com/about-cbr/cbr-family|work=cordblood.com|publisher=Cord Blood Registry|accessdate=24 June 2013}}</ref> |
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| ⚫ | CBR offers the collection, processing, and long-term cryopreservation of stem cells contained in the umbilical cord blood of newborns, as well as storage of a section of the umbilical cord.<ref>{{cite web|title=Cord Blood Registry|url=http://www.cordblood.com/best-cord-blood-bank/best-stem-cell-bank#ooid=BnaHBqMjo-LhSW9Op1nl4Vf0KbTIEvV_|work=cordblood.com|publisher=Cord Blood Registry|accessdate=9 Feb 2014}}</ref> |
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{{Infobox company|homepage = http://www.cordblood.com|industry = Biotechnology|location = San Bruno, CA|name = Cord Blood Registry}} |
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'''Cord Blood Registry''' is a biotechnology company headquartered in [[San Bruno, California]]. Founded in 1992, the company has stored more than 500,000 cord blood and cord tissue collections from 3,500 hospitals in over 100 countries and partnered with institutions on six groundbreaking FDA-regulated clinical trials. |
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| ⚫ | Moore and Grant established the CBR laboratory with David T. Harris, professor of microbiology and immunology. The project began as a pilot partially sponsored by the American Cancer Society at the [[University of Arizona]].<ref>{{cite web|last=Pangburn|first=Joe|title=Cord Blood Registry: storing the gift of second life|url=http://www.insidetucsonbusiness.com/archives/cord-blood-registry-storing-the-gift-of-second-life/article_4f684e53-398e-5a15-8412-bb00115a681b.html|work=www.insidetucsonbusiness.com|publisher=Inside Tucson Business|accessdate=24 June 2013}}</ref> |
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CBR offers the collection, processing, and long-term cryopreservation of stem cells contained in the umbilical cord blood of newborns, which is otherwise routinely discarded along with the placenta. Families have the additional option of storing a section of the umbilical cord, which contains stem cells that may help repair and heal the body in different ways than [[cord blood]]. |
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| ⚫ | Cord blood is a rich source of [[stem cells]], which have been used in the treatment of over 80 diseases, including leukemia, lymphoma and anemia.<ref>{{cite web|title=Cord Blood QA|url=http://www.nationalcordbloodprogram.org/qa/what_is_treated.html|work=nationalcordbloodprogram.org|publisher=New York Blood Center's National Cord Blood Program (NCBP)|accessdate=24 June 2013}}</ref> CBR processed cord blood has been used in clinical trials investigating conditions including: [[autism]], [[cerebral palsy]], [[hearing loss]], [[pediatric stroke]], and [[traumatic brain injury]].<ref>{{cite web|title=CBR Clinical Trials and Stem Cell Research|url=http://www.cordblood.com/stem-cell-research/cord-blood-research|work=cordblood.com|publisher=CBR Systems, Inc.|accessdate=21 January 2014}}</ref> |
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== Founding story == |
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Cord Blood Registry was founded by [http://www.cordblood.com/about-cbr/cbr-executive-team Tom Moore] and his daughter Wendy Grant.<ref>{{cite web|title=Smart Science. Healthy Families.|url=http://www.cordblood.com/about-cbr/cbr-family|work=cordblood.com|publisher=Cord Blood Registry|accessdate=24 June 2013}}</ref> In 1992, when the idea of CBR was born, the concept of storing a newborn’s umbilical cord stem cells for private family use was virtually unheard of.<ref>{{cite web|title=Cord Blood Registry|url=http://alliancerm.org/member/cord-blood-registry|work=alliancerm.org|publisher=Alliance for Regenerative Medicine|accessdate=24 June 2013}}</ref> Prior to founding CBR, Tom Moore served as founder, chairman, and CEO of [http://www.sciclone.com/ SciClone Pharmaceuticals, Inc.], the principal of Sand Hill Management Group, and CEO and chairman of Synercom Technology. |
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An article from the December 1991 issue of [[Scientific American]] sparked the idea that would become Cord Blood Registry, and an opportunity for Tom to start a father/daughter business. Wendy learned that thousands of children died each year waiting for a stem cell match and thought that starting a family bank might help families in need.<ref>{{cite web|title=Meet the Founders of Cord Blood Registry|url=http://www.youtube.com/watch?v=96DItviGvKI|work=youtube.com|publisher=CordBloodRegistry|accessdate=24 June 2013}}</ref> |
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== Transplant medicine == |
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| ⚫ | Cord blood is a rich source of [[stem cells]], which have been used in the treatment of over 80 diseases, including leukemia, lymphoma and anemia.<ref>{{cite web|title=Cord Blood QA|url=http://www.nationalcordbloodprogram.org/qa/what_is_treated.html|work=nationalcordbloodprogram.org|publisher=New York Blood Center's National Cord Blood Program (NCBP)|accessdate=24 June 2013}}</ref> |
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There are many examples of a CBR clients cured of disease or substantially improving their quality of life as a result of using stem cells stored with CBR. Joseph Davis of Cedar Hill, Texas. Mr. Davis testified before the Florida Senate Health Committee on the importance of cord blood stem cell education. He was cured of sickle cell anemia with a transplant using his younger sibling's cord blood stem cells stored at Cord Blood Registry.<ref>{{cite web|title=Understanding Your Options with Cord Blood|url=http://www.cordbloodawareness.org/|work=cordbloodawareness.org|publisher=CordBloodAwareness.org|accessdate=24 June 2013}}</ref> |
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CBR client Wendy Doheney's son Keegan was infused with his younger brother Keldan's cord blood. Doctors used the stem cells to rebuild Keegan's blood and immune system after chemotherapy and he has remained healthy.<ref>{{cite web|title=A Bond as Powerful as Cord Blood|url=http://www.cordblood.com/benefits-cord-blood/our-clients-their-stories/cord-blood-banking-reviews/leukemia-treatment|work=cordblood.com|publisher=Cord Blood Registry|accessdate=24 June 2013}}</ref> |
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In 2008, then 7-year-old Carol Mulumba was successfully infused with stem cells from her sibling's cord blood, which had been stored by Cord Blood Registry, as a treatment for sickle cell anemia.<ref>{{cite news|last=Niko|first=Kyriakou|title=Umbilical cord blood still an enigma|url=http://www.sfexaminer.com/sanfrancisco/umbilical-cord-blood-still-an-enigma/Content?oid=2178615|accessdate=24 June 2013|newspaper=The San Francisco Examiner|date=24 July 2011}}</ref> |
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== CBR executive team == |
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'''Chief Executive Officer'''<br /> |
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Geoff Crouse joined CBR as CEO in September 2012. Mr. Crouse previously served as Chief Operating Officer at Immucor, a publicly traded global in vitro diagnostics company. Prior to Immucor, Mr. Crouse served as vice president of the life sciences business at Millipore Corporation, a NYSE-traded provider of technologies, tools and services for the global life science industry. In this role, Mr. Crouse led the Life Science Strategic Business Unit, a global laboratory consumables and reagents business. Prior to joining Millipore, Mr. Crouse worked at Roche, a leader in the pharmaceuticals and diagnostics industries, where he led market development and government affairs for the diagnostics division based in Basel, Switzerland. Mr. Crouse earned a B.A. from Boston College and a M.B.A. and Masters of Public Health from the University of California at Berkeley. <ref>{{cite web|title=Geoff Crouse Chief Executive Officer|url=http://www.gtcr.com/our-investments/management-leaders/geoff-crouse/|work=gtcr.com|publisher=GTCR|accessdate=24 June 2013}}</ref> |
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'''Executive Chairman'''<br /> |
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Tom Moore is the co-founder of CBR and served as CEO from 1995-2012. Mr. Moore has more than 25 years of management experience with start-ups, including as a founder, Chairman, and Chief Executive Officer of SciClone Pharmaceuticals, Inc., a biopharmaceutical company that went public in 1992. From 1988 to 1998, Mr. Moore served as the principal of Sand Hill Management Group, a private investment and management firm involved primarily in turn-around and start-up management of high growth businesses. From 1982 to 1987, Mr. Moore was Chief Executive Officer and Chairman of Synercom Technology, a company that he took public in 1986. From 1967 to 1982, Mr. Moore held a number of senior management positions at Honeywell Inc., including Vice President of Pacific Operations. Mr. Moore holds a B.S. in Chemical Engineering from the University of California, Berkeley, and a B.S. in Finance and Marketing from California State University, Hayward. <ref>{{cite web|url=http://www.cordblood.com/about-cbr/cbr-executive-team|accessdate=22 January 2014}}</ref> |
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'''Chief Financial Officer'''<br /> |
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Mike Johnson joined CBR as CFO in January 2013. Mr. Johnson was most recently the CFO of Fenwal, a global blood technology company dedicated to supporting transfusion medicine and cell therapies. Mr. Johnson successfully managed a carve-out of the Fenwal business from Baxter in 2006. From 2006 to 2012, Mr. Johnson led the global finance and IT organizations through a business transformation that supported international integration of a stand-alone business and resulted in significant value creation. TPG, a large private equity firm, recently sold the business to Fresenius. Prior to Fenwal, Mr. Johnson spent almost 10 years in senior financial roles at Dade Behring, a leading medical diagnostics company, including Corporate Controller, and V.P. Finance for the manufacturing, supply chain and R&D organizations. Mr. Johnson brings a wealth of experience in finance, private equity, IT/IS, quality systems, and supply chain management in complex global businesses. <ref>{{cite web|url=http://www.cordblood.com/about-cbr/cbr-executive-team|accessdate=22 January 2014}}</ref> |
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'''Vice President, Science & Medical Affairs'''<br /> |
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Heather Brown has been with CBR since 2001 and has more than 20 years of clinical and business experience in the healthcare and biotech industries. Mrs. Brown is a board certified genetic counselor with extensive experience in prenatal, pediatric, and cancer genetics. Mrs. Brown has led a number of new business development and healthcare marketing initiatives during her tenure at CBR. In her current role, Mrs. Brown is primarily responsible for research partnerships, clinical trial management, and medical need-based programs. Mrs. Brown holds a B.A. and a M.S. in Health and Medical Sciences from the University of California at Berkeley. <ref>{{cite web|url=http://www.cordblood.com/about-cbr/cbr-executive-team|accessdate=22 January 2014}}</ref> |
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'''Vice President, Laboratory Operations'''<br /> |
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Kristen Swingle has been responsible for overseeing all operations at CBR’s laboratory in Tucson, Arizona, since 2007. Mrs. Swingle has a strong background in experimental design, technical writing, and management. In 2006, Mrs. Swingle served as the project lead for the implementation of AXP processing at CBR, working closely with Thermogenesis to optimize this process for CBR's facility. Before coming to CBR, Mrs. Swingle held the position of Microbiology Lab Manager for an environmental testing laboratory. Mrs. Swingle holds a B.S. in Biology and a M.S. in Medical Sciences. <ref>{{cite web|url=http://www.cordblood.com/about-cbr/cbr-executive-team|accessdate=22 January 2014}}</ref> |
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== Clinical trials == |
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Cord Blood Registry is dedicated to advancing the clinical application of newborn stem cells by partnering with leading research institutions to establish FDA-regulated clinical trials requiring CBR processed cord blood for conditions that have no cure today, including: [[autism]], [[cerebral palsy]], [[hearing loss]], [[pediatric stroke]], and [[traumatic brain injury]].<ref>{{cite web|title=CBR Clinical Trials and Stem Cell Research|url=http://www.cordblood.com/stem-cell-research/cord-blood-research|work=cordblood.com|publisher=CBR Systems, Inc.|accessdate=21 January 2014}}</ref> |
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Researchers at Sutter Neuroscience Institute in Sacramento, California, have initiated the first FDA-regulated clinical trial to assess the use of a child’s own cord blood stem cells to treat select patients with autism.<ref>{{cite web|title=Autologous Cord Blood Stem Cells for Autism|url=http://clinicaltrials.gov/ct2/show/NCT01638819|work=ClinicalTrials.gov|publisher=U.S. National Institutes of Health|accessdate=21 January 2014}}</ref> |
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Researchers at Georgia Regents University in Augusta, Georgia, have commenced the first FDA-regulated clinical trial to evaluate the use of cord blood stem cell infusions to treat children with cerebral palsy.<ref>{{cite web|title=Safety and Effectiveness of Cord Blood Stem Cell Infusion for the Treatment of Cerebral Palsy in Children|url=http://clinicaltrials.gov/ct2/show/NCT01072370|work=ClinicalTrials.gov|publisher=U.S. National Institutes of Health|accessdate=21 January 2014}}</ref> A separate FDA-regulated clinical trial for cerebral palsy is underway at the University of Texas Health Science Center in Houston, Texas. <ref>{{cite web|title=Study Will Compare the Safety and Effectiveness of Banked Cord Blood or Bone Morrow Stem Cells in Children With Cerebral Palsy|url=http://clinicaltrials.gov/ct2/show/NCT01988584|work=ClinicalTrials.gov|publisher=U.S. National Institutes of Health|accessdate=21 January 2014}}</ref> |
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Researchers at Florida Hospital for Children in Orlando, Florida, have started a FDA-regulated clinical trial to investigate the use of cord blood stem cells to treat pediatric patients with sensorineural hearing loss.<ref>{{cite web|title=Safety of Autologous Stem Cell Infusion for Children With Acquired Hearing Loss|url=http://clinicaltrials.gov/show/NCT02038972|work=ClinicalTrials.gov|publisher=U.S. National Institutes of Health|accessdate=21 January 2014}}</ref> |
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Researchers at the University of Texas Health Science Center in Houston, Texas have launched a FDA-regulated clinical trial to examine the use of cord blood stem cells for traumatic brain injury in children.<ref>{{cite web|title=Safety Study of Umbilical Cord Blood To Treat Pediatric Traumatic Brain Injury|url=http://clinicaltrials.gov/ct2/show/NCT01251003|work=ClinicalTrials.gov|publisher=U.S. National Institutes of Health|accessdate=21 January 2014}}</ref> |
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A FDA-regulated clinical trial will investigate the use of a child’s own cord blood stem cells as treatment after a pediatric stroke. |
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== References == |
== References == |
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{{reflist |
{{reflist}} |
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[[Category:Blood banks]] |
[[Category:Blood banks]] |
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Revision as of 22:59, 19 May 2014
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| Company type | Private |
|---|---|
| Founded | 1992 |
| Founder | Tom Moore and Wendy Grant |
| Headquarters | San Bruno, California 94066 , United States |
Key people | Geoff Crouse, President & CEO |
| Services | Cord blood stem cells preservation and research |
| Website | www.cordblood.com |
Cord Blood Registry is a biotechnology company headquartered in San Bruno, California, founded in 1992 by father and daughter Tom Moore and Wendy Grant.[1]
CBR offers the collection, processing, and long-term cryopreservation of stem cells contained in the umbilical cord blood of newborns, as well as storage of a section of the umbilical cord.[2]
Moore and Grant established the CBR laboratory with David T. Harris, professor of microbiology and immunology. The project began as a pilot partially sponsored by the American Cancer Society at the University of Arizona.[3]
Cord blood is a rich source of stem cells, which have been used in the treatment of over 80 diseases, including leukemia, lymphoma and anemia.[4] CBR processed cord blood has been used in clinical trials investigating conditions including: autism, cerebral palsy, hearing loss, pediatric stroke, and traumatic brain injury.[5]
References
- ^ "Smart Science. Healthy Families". cordblood.com. Cord Blood Registry. Retrieved 24 June 2013.
- ^ "Cord Blood Registry". cordblood.com. Cord Blood Registry. Retrieved 9 Feb 2014.
- ^ Pangburn, Joe. "Cord Blood Registry: storing the gift of second life". www.insidetucsonbusiness.com. Inside Tucson Business. Retrieved 24 June 2013.
- ^ "Cord Blood QA". nationalcordbloodprogram.org. New York Blood Center's National Cord Blood Program (NCBP). Retrieved 24 June 2013.
- ^ "CBR Clinical Trials and Stem Cell Research". cordblood.com. CBR Systems, Inc. Retrieved 21 January 2014.