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'''Frances Ashcroft''', [[Fellow of the Royal Society|FRS]] [[FMedSci]] (born 1952), is a British [[genetics|geneticist]] and [[ion channel]] [[physiologist]]. She is [[Royal Society]] [[GlaxoSmithKline]] Research Professor in the [[University of Oxford]]. She is a fellow of [[Trinity College, Oxford|Trinity College]] and is a director of the [[Oxford Centre for Gene Function]]. Her research group has an international reputation for work on [[insulin]] secretion, [[type II diabetes]] and [[neonatal diabetes]].<ref>{{cite doi|10.1038/312446a0}}</ref> Her work with Professor Andrew Hattersley has helped enable children born with diabetes to switch from insulin injections to tablet therapy.<ref>{{cite doi|10.1146/annurev.ne.11.030188.000525}}</ref> She attended [[Talbot Heath School]] in [[Bournemouth]], [[Dorset]].
'''Frances Ashcroft''', [[Fellow of the Royal Society|FRS]] [[FMedSci]] (born 1952), is a British [[genetics|geneticist]] and [[ion channel]] [[physiologist]]. She is [[Royal Society]] [[GlaxoSmithKline]] Research Professor at the University Laboratory of Physiology at the [[University of Oxford]]. She is a fellow of [[Trinity College, Oxford|Trinity College]] and is a director of the [[Oxford Centre for Gene Function]]. Her research group has an international reputation for work on [[insulin]] secretion, [[type II diabetes]] and [[neonatal diabetes]].<ref>{{cite doi|10.1038/312446a0}}</ref> Her work with Professor Andrew Hattersley has helped enable children born with diabetes to switch from insulin injections to tablet therapy.<ref>{{cite doi|10.1146/annurev.ne.11.030188.000525}}</ref> She attended [[Talbot Heath School]] in [[Bournemouth]], [[Dorset]].


==Honours and awards==
==Early life==
⚫
Ashcroft gained a degree in Natural Sciences, and then a PhD in zoology from Cambridge in 1978.<ref>{{cite web|url=http://www2.le.ac.uk/ebulletin/news/2000-2009/2007/07/nparticle.2007-07-16.3558954245|title=Oration for Professor Frances Ashcroft by Professor Gordon Campbell. On the occasion of being awarded Doctor of Science summer 2007.|publisher=University of Leicester|accessdate=25 June 2012}}</ref> Ashcroft then did post-doctoral research at the University of Leicester and the University of California at Los Angeles.<ref>{{cite web|url=http://www.trinity.ox.ac.uk/people/profiles/frances-ashcroft/}}</ref>
⚫
She was elected a [[Fellow of the Royal Society]] in 1999.<ref>{{cite web|url=http://royalsociety.org/about-us/fellowship/fellows|title=Lists of Royal Society Fellows 1660–2007|publisher=The Royal Society|accessdate=6 July 2012|location=London}}</ref> In 2007 she was awarded the [[Walter B. Cannon]] Award, the highest honour bestowed by the [[American Physiological Society]].<ref>{{cite news|title=Oxford physiology professor earns APS' Walter B. Cannon Award|date=27 April 2007|url=http://www.eurekalert.org/pub_releases/2007-04/aps-opp042607.php|work=EurekAlert|accessdate=27 April 2007}}</ref> She was one of five 2012 winners of the [[L'Oreal-UNESCO Award for Women in Science]].<ref>[http://www.ox.ac.uk/media/news_stories/2011/111108_3.html Ashcroft receives L'oreal-UNESCO Award for Women in Science]</ref>
She was awarded an [[honorary degree]]s of Doctor of the University from the [[Open University]] in 2003 and Doctor of Science from the [[University of Leicester]] on 13 July 2007.<ref>{{cite web|url=http://www2.le.ac.uk/ebulletin/news/2000-2009/2007/07/nparticle.2007-07-16.3558954245|title=Oration for Professor Frances Ashcroft by Professor Gordon Campbell. On the occasion of being awarded Doctor of Science summer 2007.|publisher=University of Leicester|accessdate=25 June 2012}}</ref>


==Career==
⚫
Fran Ashcroft gained her PhD from Cambridge in 1978..<ref>{{cite web|url=http://www2.le.ac.uk/ebulletin/news/2000-2009/2007/07/nparticle.2007-07-16.3558954245|title=Oration for Professor Frances Ashcroft by Professor Gordon Campbell. On the occasion of being awarded Doctor of Science summer 2007.|publisher=University of Leicester|accessdate=25 June 2012}}</ref> She was awarded an [[honorary degree]]s of Doctor of the University from the [[Open University]] in 2003 and Doctor of Science from the [[University of Leicester]] on 13 July 2007.<ref>{{cite web|url=http://www2.le.ac.uk/ebulletin/news/2000-2009/2007/07/nparticle.2007-07-16.3558954245|title=Oration for Professor Frances Ashcroft by Professor Gordon Campbell. On the occasion of being awarded Doctor of Science summer 2007.|publisher=University of Leicester|accessdate=25 June 2012}}</ref>
Ashcroft was elected a [[Fellow of the Royal Society]] in 1999.<ref>{{cite web|url=http://royalsociety.org/about-us/fellowship/fellows|title=Lists of Royal Society Fellows 1660–2007|publisher=The Royal Society|accessdate=6 July 2012|location=London}}</ref>She is a Director of OXION: Ion Channels and Disease Initiative<ref>{{cite web|url=http://oxion.dpag.ox.ac.uk/}}</ref>, a research and training programme on integative ion channel research, funded by the [[Wellcome Trust]].

== Research ==
Ashcroft's research focuses on ATP-sensitive potassium (K<sub>ATP</sub>)channels and their role in insulin secretion.
Ashcroft is working towards explaining how a rise in the blood glucose concentration stimulates the release of insulin from the pancreatic beta-cells, what goes wrong with this process in type 2 diabetes, and how drugs used to treat this condition exert their beneficial effects.<ref>{{cite web|url=http://www.dpag.ox.ac.uk/team/group-leaders/frances-ashcroft}}</ref>

==Honours and awards==
⚫
In 2007 Ashcroft was awarded the [[Walter B. Cannon]] Award, the highest honour bestowed by the [[American Physiological Society]].<ref>{{cite news|title=Oxford physiology professor earns APS' Walter B. Cannon Award|date=27 April 2007|url=http://www.eurekalert.org/pub_releases/2007-04/aps-opp042607.php|work=EurekAlert|accessdate=27 April 2007}}</ref> She was one of five 2012 winners of the [[L'Oreal-UNESCO Award for Women in Science]].<ref>[http://www.ox.ac.uk/media/news_stories/2011/111108_3.html Ashcroft receives L'oreal-UNESCO Award for Women in Science]</ref>


She delivered the [[Croonian Lecture]] at the [[Royal Society]] in 2013.<ref> {{cite web|url = http://royalsociety.org/awards/croonian-lecture/|title= Croonian Lecture|publisher= Royal Society|accessdate = 2013-09-12}} </ref>
She delivered the [[Croonian Lecture]] at the [[Royal Society]] in 2013.<ref> {{cite web|url = http://royalsociety.org/awards/croonian-lecture/|title= Croonian Lecture|publisher= Royal Society|accessdate = 2013-09-12}} </ref>

Revision as of 15:56, 14 October 2014

Frances Ashcroft
Born1952
NationalityBritish
Alma materCambridge University
Awards
Scientific career
FieldsGenetics, Physiology
Institutions
Frances Ashcroft's voice
from the BBC programme The Life Scientific, 15 May 2012.[1]

Frances Ashcroft, FRS FMedSci (born 1952), is a British geneticist and ion channel physiologist. She is Royal Society GlaxoSmithKline Research Professor at the University Laboratory of Physiology at the University of Oxford. She is a fellow of Trinity College and is a director of the Oxford Centre for Gene Function. Her research group has an international reputation for work on insulin secretion, type II diabetes and neonatal diabetes.[2] Her work with Professor Andrew Hattersley has helped enable children born with diabetes to switch from insulin injections to tablet therapy.[3] She attended Talbot Heath School in Bournemouth, Dorset.

Early life

Ashcroft gained a degree in Natural Sciences, and then a PhD in zoology from Cambridge in 1978.[4] Ashcroft then did post-doctoral research at the University of Leicester and the University of California at Los Angeles.[5] She was awarded an honorary degrees of Doctor of the University from the Open University in 2003 and Doctor of Science from the University of Leicester on 13 July 2007.[6]

Career

Ashcroft was elected a Fellow of the Royal Society in 1999.[7]She is a Director of OXION: Ion Channels and Disease Initiative[8], a research and training programme on integative ion channel research, funded by the Wellcome Trust.

Research

Ashcroft's research focuses on ATP-sensitive potassium (KATP)channels and their role in insulin secretion. Ashcroft is working towards explaining how a rise in the blood glucose concentration stimulates the release of insulin from the pancreatic beta-cells, what goes wrong with this process in type 2 diabetes, and how drugs used to treat this condition exert their beneficial effects.[9]

Honours and awards

In 2007 Ashcroft was awarded the Walter B. Cannon Award, the highest honour bestowed by the American Physiological Society.[10] She was one of five 2012 winners of the L'Oreal-UNESCO Award for Women in Science.[11]

She delivered the Croonian Lecture at the Royal Society in 2013.[12]

Bibliography

Fran Ashcroft has now authored a few science and popular science books based on ion channel physiology:

Other

She appeared (as a diner) on MasterChef during the 2011 series, along with several other Fellows of the Royal Society.

References

  1. ^ "Frances Ashcroft". The Life Scientific. 15 May 2012. BBC Radio 4. Retrieved 18 January 2014. {{cite episode}}: Unknown parameter |serieslink= ignored (|series-link= suggested) (help)
  2. ^ Attention: This template ({{cite doi}}) is deprecated. To cite the publication identified by doi:10.1038/312446a0, please use {{cite journal}} (if it was published in a bona fide academic journal, otherwise {{cite report}} with |doi=10.1038/312446a0 instead.
  3. ^ Attention: This template ({{cite doi}}) is deprecated. To cite the publication identified by doi:10.1146/annurev.ne.11.030188.000525, please use {{cite journal}} (if it was published in a bona fide academic journal, otherwise {{cite report}} with |doi=10.1146/annurev.ne.11.030188.000525 instead.
  4. ^ "Oration for Professor Frances Ashcroft by Professor Gordon Campbell. On the occasion of being awarded Doctor of Science summer 2007". University of Leicester. Retrieved 25 June 2012.
  5. ^ http://www.trinity.ox.ac.uk/people/profiles/frances-ashcroft/. {{cite web}}: Missing or empty |title= (help)
  6. ^ "Oration for Professor Frances Ashcroft by Professor Gordon Campbell. On the occasion of being awarded Doctor of Science summer 2007". University of Leicester. Retrieved 25 June 2012.
  7. ^ "Lists of Royal Society Fellows 1660–2007". London: The Royal Society. Retrieved 6 July 2012.
  8. ^ http://oxion.dpag.ox.ac.uk/. {{cite web}}: Missing or empty |title= (help)
  9. ^ http://www.dpag.ox.ac.uk/team/group-leaders/frances-ashcroft. {{cite web}}: Missing or empty |title= (help)
  10. ^ "Oxford physiology professor earns APS' Walter B. Cannon Award". EurekAlert. 27 April 2007. Retrieved 27 April 2007.
  11. ^ Ashcroft receives L'oreal-UNESCO Award for Women in Science
  12. ^ "Croonian Lecture". Royal Society. Retrieved 2013-09-12.

10 Famous Figures in Science Share their Best Tips for a Successful Career in Science Interview by Amy Hawthorne from Reagent on 11th June 2014

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