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*[http://www.aloe-vera-studies.org Aloe vera side effects - rare and mild.]
*[http://www.jaaha.org/cgi/content/abstract/31/5/439 The effect of Acemannan Immunostimulant in combination with surgery and radiation therapy on spontaneous canine and feline fibrosarcomas]
*[http://www.jaaha.org/cgi/content/abstract/31/5/439 The effect of Acemannan Immunostimulant in combination with surgery and radiation therapy on spontaneous canine and feline fibrosarcomas]
*[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=92000401&dopt=Abstract Decreased mortality of Norman murine sarcoma in mice treated with the immunomodulator, Acemannan.]
*[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=92000401&dopt=Abstract Decreased mortality of Norman murine sarcoma in mice treated with the immunomodulator, Acemannan.]

Revision as of 21:32, 29 May 2008

Aloe vera
File:Aloevera2web.jpg
Scientific classification
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A. vera
Binomial name
Aloe vera

Aloe vera (syn. A. barbadensis Mill., A. vulgaris Lam.) is a species of Aloe, native to northern Africa. It is a stemless or very short-stemmed succulent plant growing to 80–100 cm tall, spreading by offsets and root sprouts. The leaves are lanceolate, thick and fleshy, green to grey-green, with a serrated margin. The flowers are produced on a spike up to 90 cm tall, each flower pendulous, with a yellow tubular corolla 2–3 cm long.

Cultivation

Flowers

Aloe vera is relatively easy to care for in cultivation in frost-free climates. The species requires well-drained sandy potting soil in moderate light such as the sun. It may not be consumed naturally. If planted in a pot or other containers ensure sufficient drainage with drainage holes. The use of a good quality commercial potting mix to which extra perlite, granite grit, or coarse sand are added is recommended. Alternatively, pre-packaged 'cacti and succulent mixes' may also be used. Potted plants should be allowed to completely dry prior to re-watering. During winter, A. vera may become dormant, during which little moisture is required. In areas that receive frost or snow the species is best kept indoors or in heated glasshouses[citation needed].

Aloe vera has a long history of cultivation throughout the drier tropical and subtropical regions of the world, both as an ornamental plant and for herbal medicine. For its herbal and medicinal uses, many of which are shared with related species, see Aloe.

Food preservative

Researchers at the University of Miguel Hernández in Alicante, Spain, have developed a gel based on Aloe vera that prolongs the conservation of fresh produce, such as fresh fruit and legumes. This gel is tasteless, colorless and odorless. This natural product is a safe and environmentally friendly alternative to synthetic preservatives such as sulfur dioxide. The study showed that grapes at 1°C coated with this gel could be preserved for 35 days against 7 days for untreated grapes. According to the researchers, this gel operates through a combination of mechanics (Serrano et al., 2006), forming a protective layer against the oxygen and moisture of the air and inhibiting, through its various antibiotic and antifungal compounds, the action of micro-organisms that cause foodborne illnesses.

Medicinal uses

Aloe succotrina, from Koehler's Medicinal-Plants (1887)

Aloe vera has been used to treat various skin conditions such as cuts, burns and eczema. It is alleged that sap from Aloe vera eases pain and reduces inflammation. Evidence on the effects of Aloe vera sap on wound healing, however, is contradictory (Vogler and Ernst, 1999). A study performed in the 1990s showed that the healing time of a moderate to severe burn was reduced when the wound was treated on a regular basis with Aloe vera gel, compared to the healing of the wound covered in a gauze bandage (Farrar, 2005). In contrast, another study suggested wounds to which Aloe vera gel was applied were significantly slower to heal (Schmidt and Greenspoon, 1991).

Aloe vera's beneficial properties may be attributed to mucopolysaccharides present in the inner gel of the leaf, especially acemannan (acetylated mannans). An injectable form of acemannan manufactured and marketed by Carrington Laboratories as Acemannan Immunostimulant has been approved in the USA for treatment of fibrosarcoma (a type of cancer) in dogs and cats after clinical trials. It has not been approved for use by humans, and, although it is not a drug, its sale is controlled and it can only be obtained through a veterinary doctor.

Cosmetic companies add sap or other derivatives from Aloe vera to products such as makeup, tissues, moisturizers, soaps, sunscreens, shampoos and lotions, though the effectiveness of Aloe vera in these products remains unknown. Aloe vera gel is also alleged to be useful for dry skin conditions, especially eczema around the eyes and sensitive facial skin[citation needed]. Most suppliers, however, degrade the polysaccharides during processing (Turner et al, 2004).

An article published in the British Journal of General Practice suggests that Aloe vera is effective at treating athlete's foot [citation needed].

Whether or not it promotes wound healing is unknown, and even though there are some promising results, clinical effectiveness of oral or topical Aloe vera remains unclear at present.

Aloe vera juice may help some people with ulcerative colitis, an inflammatory bowel disease. Side effects can occur and consulting a doctor before ingesting any form of aloe vera, including aloe vera juice, is highly recommended.

Leaf close up

Parts that can be used

The lower leaf of the plant is used for medicinal purpose. If the lower leaf is sliced open, the gel obtained can be applied on the affected area of the skin. Leaves and seeds are the two edible parts of Aloe Vera.[citation needed]. Aloe vera latex—the yellow substance that comes from the inner side of the skin—can be highly irritating both externally and internally. Some people who have reported adverse effects from Aloe vera may be ingesting or applying this latex. Carefully removing all skin and any yellow substance before using Aloe may avoid such adverse effects. Gel used should be completely clear, odorless and tasteless.

Use in foods

In Japan, Aloe Vera is commonly used as an ingredient in commercially available yogurt. There are also many companies in East Asia which produce Aloe Vera beverages.[1]

In some of the parts of early India (British India), now Pakistan, the plant has been used for centuries as a carminative and digestive aid. The dried gel is mixed with seeds of various herbs and consumed after a meal.[citation needed]

Pashtuns in the Hazara region of the North West Frontier Province have been using Aloe Vera for centuries to improve physical endurance, probably due to the high nutrient content of the gel.[citation needed]

People in Rajasthan, India prepare Aloe Vera as a vegetable with fenugreek seeds.[citation needed]

People in Tamil Nadu another state of India prepare a curry using Aloe Vera which is taken along with Indian bread or rice.[citation needed]

Some popular beverages, such as SoBe's Strawberry Daiquirí, contain Aloe Vera. In Mexico smoothies made out of Aloe Vera are fairly common.[citation needed]

In South Korea Aloe Vera is an ingredient in a popular soft drink, manufactured by the Hosan Corporation, called Aloe Drink "Aloe Vera Drinks"..

The outer leaf also contains alpha/beta quinones. Often called a glycoside and laxative this molecule has received much attention in recent years. Reported through separate, independant laboratory studies quinones are shown to increase cell membrane permiability in leukemia cell lines as well as other cancer cell lines, (in vitro.)[2]

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References