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Toothpaste from a tube being applied to a toothbrush

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 [[Image:Toothpasteonbrush.jpg|thumb|Toothpaste from a tube being applied to a toothbrush]]
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-'''Toothpaste''' is a [[paste]] or [[gel]] [[dentifrice]] used to clean and maintain the aesthetics and health of [[teeth]]. Toothpaste is used to promote [[oral hygiene]]: it can aid in the removal of [[dental plaque]] and [[food]] from the teeth, aid in the elimination and/or masking of [[halitosis]] and  deliver active ingredients such as [[fluoride]] or [[xylitol]] to prevent tooth and gum disease ([[gingivitis]]).  In most or all [[developed countries]], usage after each meal is encouraged. Most toothpaste contains chemicals which are toxic when ingested, and is not intended to be swallowed.
-==History==
-===Early toothpastes===
-The earliest known reference to a toothpaste is in a chart from [[Italy]] in the 4th century AD, which prescribes a mixture of powdered [[salt]], [[black pepper|pepper]], [[mentha|mint]] leaves, and [[iris (plant)|iris]] flowers. The [[Ancient Greece|Greeks]], and then the [[Ancient Rome|Romans]], improved the recipes for toothpaste by adding abrasives such as crushed bones and oyster shells.<ref>[http://www.bbc.co.uk/dna/h2g2/A2818686 The History of Toothpaste and Toothbrushes]</ref> The Romans used toothpaste formulations based on human [[urine]].<ref>[http://www.toothpasteworld.com/history.htm Toothpasteworld - Toothpaste History]</ref><ref name="Ingredients">{{citeweb|url=http://www.beautyriot.com/article.php?id=2102&c_id=9|title=Ingredients in toothpaste|accessdate=2007-12-23}}</ref> In the 9th century, the [[Persian people|Persian]] musician and fashion designer [[Ziryab]] is known to have invented a type of toothpaste, which he popularized throughout [[Al-Andalus|Islamic Spain]].<ref name=Sertima/> The exact ingredients of this toothpaste are currently unknown,<ref>{{citation|last=Lebling Jr.|first=Robert W.|title=Flight of the Blackbird|journal=[[Saudi Aramco World]]|date=July-August 2003|pages=24–33|url=http://www.islamicspain.tv/Arts-and-Science/flight_of_the_blackbird.htm|accessdate=2008-01-28}}</ref> but it was reported to have been both "functional and pleasant to taste".<ref name=Sertima>{{citation|last=Sertima|first=Ivan Van|authorlink=Ivan Van Sertima|year=1992|title=The Golden Age of the Moor|page=267|publisher=[[Transaction Publishers]]|isbn=1560005815}}</ref> It is not known whether these early toothpastes were used alone, were to be rubbed onto the teeth with rags, or were to be used with early toothbrushes such as [[neem tree]] twigs or ''[[miswak]]''. It is known that these twigs were used by Indians from ancient times. Neem tree twigs are said to have good medicinal effects.
-===Tooth powder===
-Tooth powders for use with toothbrushes came into general use in the 19th century in [[United Kingdom|Britain]].  Most were homemade, with [[chalk]], pulverized [[brick]], or [[salt]] as ingredients. An 1866 Home Encyclopedia recommended pulverized [[charcoal]], and cautioned that many patented tooth powders that were commercially marketed did more harm than good.{{Fact|date=August 2007}}
-===Modern toothpaste===
-[[Image:Toothpaste.jpg|thumb|Modern toothpaste gel]]
-An [[18th century]] American and British toothpaste recipe containing burnt bread has been found.  Another formula around this time called for [[dragon's blood]] (a resin),  [[cinnamon]], and burnt [[alum]].<ref name="Ingredients 2">{{citeweb|url=http://www.toothpasteworld.com/history.htm|title=Other ingredients in toothpaste|accessdate=2007-12-23}}</ref>
-By 1900, a paste made of [[hydrogen peroxide]] and [[baking soda]] was recommended for use with toothbrushes. Pre-mixed toothpastes were first marketed in the 19th century, but did not surpass the popularity of tooth-powder until [[World War I]]. In 1892, [[Sheffield_Pharmaceuticals|Dr. Washington Sheffield]] of New London, Connecticut, manufactured toothpaste into a collapsible tube. Sheffield's toothpaste was called Dr. Sheffield's Creme Dentifrice. He had the idea after his son traveled to Paris and saw painters using paint from tubes.  In [[New York City]] in 1896, [[Colgate-Palmolive|Colgate & Company]] Dental Cream was packaged in collapsible tubes imitating Sheffield.
-[[Fluoride]] was first added to toothpastes in 1914, and was criticized by the [[American Dental Association]] (ADA) in 1937. Fluoride toothpastes developed in the 1950s received the ADA's approval. To develop the first ADA-approved fluoride toothpaste, [[Procter & Gamble]] started a research program in the early 1940s. In 1950, Procter & Gamble developed a joint research project team headed by Dr. Joseph Muhler at Indiana University to study new toothpaste with fluoride. In 1955, Procter & Gamble's [[Crest (toothpaste)|Crest]] launched its first clinically proven fluoride toothpaste. On August 1, 1960, the ADA reported that "Crest has been shown to be an effective anticaries (decay preventative) dentifrice that can be of significant value when used in a conscientiously applied program of oral hygiene and regular professional care." Countries limit and suggest different amounts of fluoride acceptable for health. Much of [[Africa]] has a slightly higher percentage than the [[United States|U.S.]] {{Fact|date=April 2007}}
-In June, 2007, the US [[Food and Drug Administration]] and similar agencies in [[Panama]], [[Puerto Rico]] and [[Australia]] advised consumers to avoid certain brands of toothpaste manufactured in [[Peoples Republic of China|China]], after some were found to contain the poisonous [[diethylene glycol]], also called diglycol or labeled as "DEG" on the tube. The chemical is used in [[antifreeze]] as a solvent and is potentially fatal.<ref name="Chinese toothpaste">{{citeweb|url=http://www.msnbc.msn.com/id/18985512/|title=MSNBC: Throw away Chinese toothpaste, FDA warns|accessdate=2007-12-23}}</ref>
-Toothpaste is most commonly sold in flexible [[tube]]s, though containers are available. The hard containers stand straight up, availing more of the toothpaste and saving shelf space.  Because toothpaste tubes are now usually plastic, the easiest way to get the last bit out of the seemingly empty tube is simply to cut it open with scissors.  Most tubes have enough paste available for 10-30 more brushes.  If you cut it across the tube 2/3 from the end, the other 1/3 forms a natural almost airtight cap.
-==Ingredients and flavors==
-===Active ingredients===
-[[Fluoride]] in various forms is the most popular active ingredient in toothpaste to prevent cavities. Although it occurs in small amounts in plants and animals, and has effects on the formation of dental enamel and bones, it is not considered to be a dietary essential and no deficiency signs are known. [[Sodium fluoride]] (NaF) is the most common form; some brands use [[sodium monofluorophosphate]] (Na<sub>2</sub>PO<sub>3</sub>F). Much of the toothpaste sold in the United States has 1000 to 1100 parts per million fluoride ion from one of these active ingredients, in the UK the fluoride content is often higher, a NaF of 0.32% w/w (1,450 [[Parts-per notation|ppm]] fluoride) is not uncommon. This consistency leads some to conclude that cheap toothpaste is just as good as expensive toothpaste. When the magazine [[Consumer Reports]] rated toothpastes in 1998, 30 of the 38 were judged excellent. Application of fluoride also prevents moisture build-up in some surfaces.{{Fact|date=February 2007}}
-Other ingredients are less commonly used, including [[Hydroxyapatite]] [[nanocrystal]]s and [[calcium phosphate]] for [[remineralization]],<ref>[http://www.dentist.net/amorphous-calcium-phosphate2.asp Calcium Phosphate Technologies from dentist.net<!-- Bot generated title -->]</ref> and [[strontium chloride]] or [[potassium nitrate]] to reduce sensitivity.
-===Other ingredients===
-In addition to fluoride, the other fundamental ingredient in most toothpastes is an abrasive.{{Fact|date=February 2007}}  Studies have shown that abrasives in toothpaste reduce the time needed to remove plaque from the teeth by approximately 50%.  Abrasives, like the dental polishing agents used in dentist's offices, also cause a small amount of enamel erosion which is termed "polishing" action.  Some brands contain powdered white [[mica]] which acts as a mild abrasive, and also adds a cosmetically-pleasing glittery shimmer to the paste. Many may contain frustules of dead [[diatoms]] as a mild abrasive. The removal of plaque and calculus prevents caries and periodontal disease.  The polishing of teeth removes stains from tooth surfaces, but has not been shown to improve dental health over and above the effects of the removal of plaque and calculus.
-Many, though not all, toothpastes contain [[sodium dodecyl sulfate|sodium lauryl sulfate (SLS)]] or another of the sulfate family. SLS is found in other personal care products as well, such as shampoo, and is largely a foaming agent although it also acts as a powerful antimicrobial. Due to the anionic charge of SLS, mouthwashes containing cetylpyridinium chloride (which has a cationic charge and thus neutralises SLS) should not be used straight after brushing. SLS may cause a greater frequency of [[mouth ulcer]]s in some people as it can dry out the protective layer of oral tissues causing the underlying tissues to become damaged[http://www.dentalgentlecare.com/cancer_sores_copy(1).htm].
-Ingredients such as [[baking soda]], [[enzymes]], [[vitamins]], [[herbs]], [[calcium]], [[calcium sodium phosphosilicate]], [[mouthwash]], and/or [[hydrogen peroxide]] are often combined into base mixes and marketed as being beneficial. Some manufacturers add antibacterial agents, for example [[triclosan]] or [[zinc chloride]], to prevent gingivitis. Triclosan is a common ingredient in the UK.
-Toothpaste comes in a variety of [[food coloring|colorings]], and [[flavor]]s. The more usual flavorings are some variation on [[mentha|mint]] ([[spearmint]], [[peppermint]], regular mint, etc). Other more exotic flavors include: [[anise]], [[apricot]], [[bubblegum]], [[cinnamon]], [[fennel]], [[neem]], [[ginger]], [[vanilla]], [[lemon]], [[orange (fruit)|orange]], [[pine]]. More unusual are flavors include [[peanut butter]], [[iced tea]], and even [[whisky]]. Unflavored toothpaste does exist, however, most are flavored and sweetened. Because [[sugar]] promotes growth of bacteria that cause tooth decay, artificial sweeteners are generally used instead. The inclusion of sweet-tasting but toxic [[diethylene glycol]] in Chinese-made toothpaste led to a multi-nation and multi-brand toothpaste recall in 2007.
-===Toxicity===
-With the exception of toothpaste intended to be used on pets such as dogs and cats, and toothpaste used by [[astronaut]]s, most toothpaste is not intended to be swallowed, and doing so may cause [[nausea]] or [[diarrhea]]; fluoride toothpaste can be toxic if swallowed in large amounts. If a large amount of toothpaste is swallowed, Poison Control should be contacted immediately.{{Fact|date=August 2008}} Extended consumption while the teeth are forming can result in [[Dental fluorosis|fluorosis]]. This is why young children should not use fluoride toothpaste except under close supervision. There are several non-fluoride toothpaste options available in the market for those who choose not to use fluoride. Natural toothpaste can contain peppermint oil, myrrh, plant extract(strawberry extract), special oils and cleansing agents.
-==Striped toothpaste==
-{| align="right"
-|[[Image:tooth-paste-stripes.jpg|thumb|How stripes are produced in toothpaste]]
-|}
-Striping of toothpaste can be solely for the purpose of providing an alternative appearance or for the delivery of pastes requiring the reaction of two or more components that need to be kept separate until use.
-Striped toothpaste can be produced by including two different colored toothpastes in an unusual type of packaging. The collapsible [[tube]] has two tanks, one filled with each color paste (see figure). Squeezing the tube pushes the two pastes out the opening.  The tube nozzle layers the pastes to produce a striped pattern. As the tube is squeezed, the stripes flow parallel to each other and do not mix.  The patterned paste that gets dispensed is simply a narrower version of what is in the tube.  Filling is done using a multi-nozzle filling head that dispenses a different colored stripe in each direction.  To keep the stripes parallel to the axis of the tube, the head starts at the bottom and retracts as it fills, staying just above the level of the paste.  Tubes with two compartments are generally reserved for toothpastes containing two formulas intended to react together and therefore kept isolated until dispensed (e.g. Colgate Simply White). To keep the cost of packaging to a minimum, it is now common for tubes to be filled with striped paste (e.g. Aquafresh).[http://www.aquafresh.com]
-== See also ==
-* [[Tooth whitening]]
-* [[Dental floss]]
-* [[Fluoride therapy]]
-* [[Sodium dodecyl sulfate]]
-* [[Toothbrush]]
-* [[Creamy snuff]]
-==References==
-{{reflist}}
-==External links==
-*[http://www.fluoride-history.de/p-dentifrice.htm Fluoride toothpaste history]
-[[Category:Dentifrices]]
-[[Category:Oral hygiene]]
-[[Category:Teeth]]
-[[Category:Oral pathology]]
-[[Category:Brands of toothpaste]]
-[[ar:معجون أسنان]]
-[[zh-min-nan:Khí-ko]]
-[[ca:Pasta de dents]]
-[[cs:Zubní pasta]]
-[[da:Tandpasta]]
-[[de:Zahnpasta]]
-[[et:Hambapasta]]
-[[es:Pasta de dientes]]
-[[eo:Dentopasto]]
-[[fr:Dentifrice]]
-[[gd:Uachdar-fhiaclan]]
-[[ko:치약]]
-[[id:Pasta gigi]]
-[[it:Dentifricio]]
-[[he:משחת שיניים]]
-[[hu:Fogkrém]]
-[[nl:Tandpasta]]
-[[ja:歯磨剤]]
-[[no:Tannkrem]]
-[[nn:Tannkrem]]
-[[pl:Pasta do zębów]]
-[[pt:Creme dental]]
-[[ro:Pastă de dinţi]]
-[[ru:Зубная паста]]
-[[sk:Zubná pasta]]
-[[su:Pasta huntu]]
-[[fi:Hammastahna]]
-[[sv:Tandkräm]]
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-[[th:ยาสีฟัน]]
-[[vi:Kem đánh răng]]
-[[wuu:牙膏]]
-[[zh-yue:牙膏]]
-[[zh:潔齒劑]]