Talk:Sirolimus

Should the drug really be listed as its trade name, rather than the common chemical one?

    I agree, all other drug articles i've seen on WP are under their chemical name, not their trade name, especially since the trade name can differ across countries. --81.205.3.113 (talk) 00:39, 15 July 2009 (UTC)

btavshanjian

Autism section

Is retardism really the best terminology to be used here? —Preceding unsigned comment added by 90.152.14.118 (talk) 09:16, 25 September 2008 (UTC)

I don't think so personally. Standard IQ tests that are used to diagnose and define retardation unfortunately rely heavily on verbal skills. If there is anyone out there that knows of a testing method that defines congnitive ability independantly of verbal skill, I would like to hear of it. It is unfair to those affected by ASD to not separate the two. How to do that may be another question!Melanie.brown35 (talk) 22:19, 29 January 2009 (UTC)

Structure?

Is the stereochemistry of the structure correct? I'm finding differences in online structures as to what the stereochemistry to the methyl group near the lactone should be. (Hashed bond in upper left) (Also posted on image talk page)-- 16:07, 31 January 2007 (UTC)

I created the image using Image:Sirolimus1.gif as a model, then checked it for accuracy against CID 6436030 from PubChem. If the stereochemistry is inaccurate, I apologize; I'll try to find alternate sources and re-check. Fvasconcellos 22:51, 31 January 2007 (UTC)

Apparently it was incorrect. Fixed now, as is the IUPAC name—the one previously in the article was actually for tacrolimus. Thank you. Fvasconcellos 01:25, 1 February 2007 (UTC)

Gimrudghk (talk) 01:25, 27 July 2008 (UTC)Silorimus have several side effects. For example anemia, edema etc.

Sirolimus/ Late Thrombosis

Inclusion of the statement of the rapamycin DES stent (known as Cypher and sometimes denoted as SES) may be misleading since the exact reason is debatable. One postulate includes what Dr. Renu Virmani at Armed Forces Reseach Laboratories calls a polymer hypersensitivity. If this is correct, then the statement should be included on a Wikipedia page on the Cypher stent and not on the rapamycin/sirolimus page. CClaude 216.140.123.24 (talk) 20:00, 2 December 2008 (UTC)

More precise longevity statement

"A 2009 study indicated that rapamycin can prolong the life of mice. If this increase in lifespan were translated to human years, it might allow humans to live more than a hundred years". That could use a rewrite. Something like, "If these results were replicable in humans, average lifespan could be extended to over 100 years." 206.223.190.7 (talk) 22:46, 9 July 2009 (UTC)