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Disease

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A disease is an abnormal condition of an organism that impairs bodily functions,[1] associated with specific symptoms and signs.[2][3]

In human beings,"disease" is often used more broadly to refer to any condition that causes discomfort, dysfunction, distress, social problems, and/or death to the person afflicted, or similar problems for those in contact with the person. In this broader sense, it sometimes includes injuries, disabilities, disorders, syndromes, infections, isolated symptoms, deviant behaviors, and atypical variations of structure and function, while in other contexts and for other purposes these may be considered distinguishable categories.[citation needed]

Classifying a condition as a disease is a social act of valuation, and may change the social status of the person with the condition (the patient). Some conditions (known as culture-bound syndromes) are only recognized as diseases within a particular culture. Sometimes the categorization of a condition as a disease is controversial within the culture.


Related concepts

The terms disease, disorder, medical condition are often used interchangeably. There is no agreed-upon universal distinction between these terms, though some people do make distinctions in particular contexts.

Medical usage sometimes distinguishes a disease, which has a known specific cause or causes (called its etiology), from a syndrome, which is a collection of signs or symptoms that occur together. However, many conditions have been identified, yet continue to be referred to as "syndromes." Furthermore, numerous conditions of unknown etiology are referred to as "diseases" in many contexts. Refractory diseases do not respond to therapy by overcoming the resistance to drugs.

Illness, although often used to mean disease,[4] can also refer to a person's perception of their health, regardless of whether they in fact have a disease. A person without any disease may feel unhealthy and simply have the perception of having a disease. Another person may feel healthy with similar perceptions of perfectly good health. The individual's perception of good health may even persist with the medical diagnosis of having a disease; for example, such as dangerously high blood pressure, which may lead to a fatal heart attack or stroke.

Pathology is the study of diseases. The subject of systematic classification of diseases is referred to as nosology. A disease's cause is referred to as its etiology. The broader body of knowledge about human diseases and their treatments is medicine. Many similar (and a few of the same) conditions or processes can affect non-human animals (wild or domestic). The study of diseases affecting animals is veterinary medicine.

Disease can be thought of as the presence of pathology, which can occur with or without subjective feelings of being unwell or social recognition of that state. Illness as the subjective state of "unwellness" can occur independently of, or in conjunction with, disease or sickness (with sickness the social classification of someone deemed diseased, which can also occur independently of the presence or absence of disease or illness (c.f. subjective medical conditions). Thus, someone with undetected high blood pressure who feels to be of good health would be diseased, but not ill or sick. Someone with a diagnosis of late-stage cancer would be diseased, probably feeling quite ill, and recognized by others as sick. A person incarcerated in a totalitarian psychiatric hospital for political purposes could arguably be then said to not be diseased, nor ill, but only classified as sick by the rulers of a society with which the person did not agree. Having had a bad day after a night of excess drinking, one might feel ill, but one would not be diseased, nor is it likely that a boss could be convinced of the sickness.

Transmission of disease

Main article: Transmission (medicine)

Some diseases such as influenza are contagious and infectious. Infectious diseases can be transmitted by any of a variety of mechanisms, including aerosols produced by coughs and sneezes, by bites of insects or other carriers of the disease, and from contaminated water or food (possibly by faeces), etc. Also, there are sexually transmitted diseases. When micro-organisms that cannot be spread from person to person might play a role, some diseases can be prevented with proper nutrition. Other diseases such as cancer and heart disease are not considered to be caused by infection. The same is true of mental diseases.

Social significance of disease

Living with disease can be very difficult. The identification of a condition as a disease, rather than as simply a variation of human structure or function, can have significant social or economic implications. The controversial recognitions as diseases of post-traumatic stress disorder, also known as "Soldier's heart," "shell shock," and "combat fatigue;" repetitive motion injury or repetitive stress injury (RSI); and Gulf War syndrome has had a number of positive and negative effects on the financial and other responsibilities of governments, corporations and institutions towards individuals, as well as on the individuals themselves. The social implication of viewing aging as a disease could be profound, though this classification is not yet widespread.

A condition may be considered to be a disease in some cultures or eras but not in others. Oppositional-defiant disorder[citation needed], attention-deficit hyperactivity disorder[citation needed], and, increasingly, obesity[citation needed], are conditions considered to be diseases in the United States and Canada today, but were not so-considered decades ago and are not so-considered in some other countries[attribution needed]. Lepers were a group of afflicted individuals who were historically shunned and the term "leper" still evokes social stigma. Fear of disease can still be a widespread social phenomena, though not all diseases evoke extreme social stigma.

Sickness confers the social legitimization of certain benefits, such as illness benefits, work avoidance, and being looked after by others. In return, there is an obligation on the sick person to seek treatment and work to become well once more. As a comparison, consider pregnancy, which is not a state interpreted as disease or sickness by the individual. On the other hand, it is considered by the medical community as a condition requiring medical care and by society at large as a condition requiring one's staying at home from work.

Global burden of disease

Main article: Global burden of disease

This chart, compiled in 2002 from the global burden of disease study performed by the World Health Organization shows an overview of the impact of various classifications of disease, segregated by regions with low and high mortality:

File:GlobalBurdenOfDisease2002.PNG

See also

References

  1. ^ WordNet Search - 3.0
  2. ^ eMedicine/Stedman Medical Dictionary Lookup!
  3. ^ "12300762" at Dorland's Medical Dictionary
  4. ^ eMedicine/Stedman Medical Dictionary Lookup!

External links

Look up disease in Wiktionary, the free dictionary.
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