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Vitamin U

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Vitamin U is a synonym for methylmethionine sulfonium chloride.[1] The term was coined in 1949 by Garnett Cheney for then-unidentified fat-soluble factors in raw cabbage juice that were reported to speed the healing peptic ulcers (in eleven days versus thirty-seven for placebo).[2][3][4] S-methylmethionine is only one of the beneficial compounds in these plants.[5] Other research points to fibre preventing ulcers.[6] Glucosinolate is a group of molecules in the Brassicaceae family with gastro- and hepato-protective action.[7] Indoles and iso-thio-cyanates dominate effects of Brassicaceae in this article, because they are products of glucosinolate decomposition.

Gastroenterology

Without myrosinase, bacteria in the rat cecum can hydrolyse glucoraphanin into raphanin.[8] Allyl-iso-thio-cyanate (AITC) increases food transit time in rat colons.[9] Sulforaphane enhances protection and repair of gastric mucosa in vitro.[10] DIM has many molecular targets and dramatic effects against ulcerative colitis and colon cancer in what lives.[11]

Hepatology

While Brassicaceae is a large family of plants containing hepato-protective agents,[12] it does not contain a monopoly on them.[13]

Oncology

I3C promotes cancer cell death in vitro with many molecular targets on breast, prostate, endometrium, colon, and leukocytes.[14] Broccoli sprouts are rich enough in glucoraphanin for experimental results against aflatoxin, a carcinogen.[15] Ulyasov and others found positive results in leukemia with DIM,[16] Glucobrassicin being a precursor of DIM through indole-3-carbinol.

Microbiology

Iso-thio-cyanates are an important factor in the action of Wasabi against Helicobacter Pylori,[17][18][19] and ITC is not a molecule, but a functional group on many different molecules, Sinigrin being a notable precursor of allyl-ITC, and AITC being a larger part of Wasabi than of most other Brassicaceae. Sulforaphane demonstrates anti-inflammatory effects on Helicobacter pylori-infected gastric mucosae in mice and human subjects.[10]

Contraindications

Brassica species probably cause baby colic in breast-feeding.[20]

References

  1. ^ National Center for Biomedical Ontology. "Methylmethionine Sulfonium Chloride".
  2. ^ Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 18104715, please use {{cite journal}} with |pmid=18104715 instead.
  3. ^ Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 3010497, please use {{cite journal}} with |pmid=3010497 instead.
  4. ^ Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 5839761, please use {{cite journal}} with |pmid=5839761 instead.
  5. ^ http://realfoodforager.com/6-reasons-to-drink-fermented-cabbage-juice/
  6. ^ Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 20166992, please use {{cite journal}} with |pmid=20166992 instead.
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  10. ^ a b Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 21548875, please use {{cite journal}} with |pmid=21548875 instead.
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  17. ^ Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 15246236, please use {{cite journal}} with |pmid=15246236 instead.[unreliable medical source?]
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  20. ^ Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 8537569, please use {{cite journal}} with |pmid=8537569 instead.[unreliable medical source?]

Further reading

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