Talk:Pyrimethamine

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Why is it specific to protozoa

Why is Pyrimethamine use only to treat protozoal infections ? Presumably (from the mechanism) it also has antibacterial and anti-cancer properties ? Rod57 (talk) 19:15, 5 January 2009 (UTC)[reply]

Fansidar

Why is this not listed as a brand name, or as an alternative antimalarial? Certainly this packaging has relevance in terms of availability of the drug, no? Why is it relegated to a footnote in references, not even See Also? DAVilla (talk) 02:37, 20 September 2015 (UTC)[reply]

Beats me, DAVilla. I inserted Fansidar, so it doesnt need to be in a see also section. you could have done it too....many of these antibiotic articles are in less than desirable shape.--Wuerzele (talk) 03:04, 20 September 2015 (UTC)[reply]

Mixup in the synthesis scheme

In the synthesis scheme there is trimethyl orthoformate used for the methylation instead of diazomethane. Maybe the person who made the scheme could correct this? I guess this would be faster than drawing the whole thing new from scratch.129.206.54.17 (talk) 17:11, 21 September 2015 (UTC)[reply]

History?

Some news reports are saying this drug is 62 years old.

It could no longer be under patent then but some how the rights to it have been purchased in 2015.

What is the true timeline of this drugs development? — Preceding unsigned comment added by 23.119.204.117 (talk) 19:32, 21 September 2015 (UTC)[reply]

I have a found a report in The Times on 25 August 1953 which attributes the discovery of pyrimethamine to the Wellcome Foundation Ltd, specifically their laboratory at Tuckahoe in New York. It was then trialled by the Wellcome Laboratories of Tropical Medicine in London. The report also mentions that investigation and development took nine years in all. Emma May Smith (talk) 22:15, 21 September 2015 (UTC)[reply]