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Hendrik Streeck

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Hendrik Streeck, M.D. (* 7. August 1977 in Göttingen) is a German HIV research, epidemiologist and clinical trialist. He is professor for medical biology and the director of the Institute for HIV Research at the University of Duisburg-Essen.[1][2]

Career

Hendrik Streeck studied medicine at the Charite University, Berlin and obtained his PhD from the University of Bonn, which he performed part-time at the Partners AIDS Research Center, Massachusetts General Hospital,  Harvard Medical School. After his graduation he started to work as a postdoctoral fellow at the Ragon Institute of MGH, MIT and Harvard. In 2009 he was promoted to Instructor in Medicine and in 2011 to Assistant Professor at Harvard Medical School. Im September 2012 he was recruited to the United States Military HIV Research Program, Bethesda, where he became the Chief of the Cellular Immunology Section as well as Assistant Professor at the Uniformed Services University of Health Sciences and adjunct faculty of the Bloomberg School of Public Health, Johns Hopkins University[3]. In 2015 he became the Chair for Medical Biology at the University Duisburg-Essenand founded the Institute for HIV Research in the same year[4][5][6][7]. He still remains the status of „visiting scientist” US Military HIV Research Program. In 2018 he was named to be on the advisory board of the German AIDS Foundation (Deutsche AIDS Stiftung)[8].

Work

Under his direction the Institute for HIV Research works on several prevention methods against HIV including the development and feasibility of HIV vaccines as well as Pre-exposure prophylaxis (PrEP)[9][10][11]. A particular focus for HIV vaccine development is to understand how T follicular helper (Tfh) cells can drive protective antibody responses during the germinal center reaction. Further research areas of the institute include to understand why some comorbidities such as cancer or cardiovascular diseases are more prone to develop in chronic HIV infection and whether strategies can be developed to suppress HIV viral loads in the absence of antiretroviral therapy. Some of these studies are being performed in Maputo, Mozambique, where he leads a PhD sandwich program with the Instituto Nacionale de Saude to train and retain young physician scientists[12]. Besides HIV Hendrik Streeck actively investigates the epidemiology, novel prevention and treatment options of other sexually transmitted infections (STI)[13]. Currently, he conducts the largest systematic study for STIs in Germany (BRAHMS study to understand) who is becoming infected with which STI.

In January 2019 the Study was expanded to other European countries including France, Italy, Spain, Poland and Hungary under the name STIPnet study. In parallel a European HIV & STI prevention network will be established[14][15].

Awards

2009                           HIV/AIDS Award of the German AIDS Society (DAIG)[16]

2014                           Else Kröner-Fresenius-Award to recruit elite scientists to Germany[17]

Books/Chapters

  • H. Streeck, G. Alter: "Immune Responses to Viral Infections." In: D. D. Richman, J. Whitley, F. G. Hayden: Clinical virology. 4. edition. ASM Press, 2016, ISBN 978-1-55581-942-2
  • H. Streeck: Bug Attack (The Adventures of Damien the CD4 Cell & his Friends).Band 1, ISBN 1-5052-4534-6< . (children book, age 3–6 years, English)

Publications (selection)

B. T. Schultz, A. F. Oster, F. Pissani, J. E. Teigler, G. Kranias, G. Alter, M. Marovich, M. A. Eller, U. Dittmer, M. L. Robb, J. H. Kim, N. L. Michael, D. Bolton, H. Streeck: "Circulating HIV-Specific Interleukin-21+CD4+ T Cells Represent Peripheral Tfh Cells with Antigen-Dependent Helper Functions." In: Immunity. 2016.

F. Pissani, H. Streeck: "Emerging concepts on T follicular helper cell dynamics in HIV infection" In: Trends in Immunology. 35(6), Jun 2014, S. 278–286.

 S. Ranasinghe, S. Cutler, I. Davis, R. Lu, D. Z. Soghoian, Y. Qi, J. Sidney, G. Kranias, M. D. Flanders, M. Lindqvist, B. Kuhl, G. Alter, S. G. Deeks, B. D. Walker, X. Gao, A. Sette, M. Carrington, H. Streeck: "Association of HLA-DRB1-restricted CD4⁺T cell responses with HIV immune control." In: Nature Medicine . 19(7), Jul 2013, S. 930–933.

M. Lindqvist, J. van Lunzen, D. Z. Soghoian, B. D. Kuhl, S. Ranasinghe, G. Kranias, M. D. Flanders, S. Cutler, N. Yudanin, M. I. Muller, I. Davis, D. Farber, P. Hartjen, F. Haag, G. Alter, J. Schulze zur Wiesch, H. Streeck: "Expansion of HIV-specific T follicular helper cells in chronic HIV infection" In: Journal of Clinical Investigation. 122(9), 4. Sep 2012, S. 3271–3280.

M. F. Chevalier, B. Jülg, A. Pyo, M. Flanders, S. Ranasinghe, D. Z. Soghoian, D. S. Kwon, J. Rychert, J. Lian, M. I. Muller, S. Cutler, E. McAndrew, H. Jessen, F. Pereyra, E. S. Rosenberg, M. Altfeld, B. D. Walker, H. Streeck: "HIV-1-specific interleukin-21+ CD4+ T cell responses contribute to durable viral control through the modulation of HIV-specific CD8+ T cell function." In: Journal of Virology. 85(2), Jan 2011, S. 733–741.

H. Streeck, B. Li, A. F. Poon, A. Schneidewind, A. D. Gladden, K. A. Power, D. Daskalakis, S. Bazner, R. Zuniga, C. Brander, E. S. Rosenberg, S. D. Frost, M. Altfeld, T. M. Allen: "Immune-driven recombination and loss of control after HIV superinfection" In: Journal of Experimental Medicine. 205(8), 4. Aug 2008, S. 1789–1796.

References

  1. ^ "Institut für HIV-Forschung". www.uni-due.de. Retrieved 2019-01-07.
  2. ^ "Institute for HIV Research". Institute for HIV Research (in German). Retrieved 2019-01-07.
  3. ^ "MHRP Welcomes Dr. Hendrik Streeck". MHRP | Military HIV Research Program. Retrieved 2019-01-07.
  4. ^ Welle (www.dw.com), Deutsche. "Germany's first dedicated HIV research hub opens in 'exciting times' for vaccine | DW | 16.11.2016". DW.COM. Retrieved 2019-01-07.
  5. ^ "Prof. Dr. Hendrik Streeck". HuffPost Deutschland (in German). Retrieved 2019-01-07.
  6. ^ "Hendrik Streeck". Institute for HIV Research. Retrieved 2019-01-07.
  7. ^ King, Mark S. (2015-01-06). "15 HIV Advocates to Watch in 2015". My Fabulous Disease. Retrieved 2019-01-07.
  8. ^ AIDS-Stiftung, Deutsche. "HIV-Impfstoffforscher Hendrik Streeck ins Kuratorium der Deutschen AIDS-Stiftung berufen". Deutsche AIDS-Stiftung (in German). Retrieved 2019-01-07.
  9. ^ "Professor Hendrik Streeck: «HIV vaccine would be the best solution»". Platforma. 2018-02-27. Retrieved 2019-01-07.
  10. ^ "New HIV Cohort Study Opens In Germany". MHRP | Military HIV Research Program. Retrieved 2019-01-07.
  11. ^ programme.aids2018.org http://programme.aids2018.org/Abstract/Abstract/4768. Retrieved 2019-01-07. {{cite web}}: Missing or empty |title= (help)
  12. ^ "Meldungen aus der UDE". www.uni-due.de. Retrieved 2019-01-07.
  13. ^ "BRAHMS Info". Institute for HIV Research. Retrieved 2019-01-07.
  14. ^ "STIPnet: European HIV & STI Prevention Network". Retrieved 2019-01-07.
  15. ^ "Collaboration to understand the HIV & STI epidemics in Europe". www.alphagalileo.org. Retrieved 2019-01-07.
  16. ^ "Dr. Hendrik Streeck erhält den Forschungspreis der Deutschen AIDS-Gesellschaft 2009 — Deutsche AIDS Gesellschaft e.V." {{cite journal}}: Cite journal requires |journal= (help)
  17. ^ "Aidsforscher kommt aus USA an die UDE - German Scholars Organization e.V." www.gsonet.org. Retrieved 2019-01-07.
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