(+)-camphene synthase
Appearance
(+)-camphene synthase | |||||||||
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Identifiers | |||||||||
EC no. | 4.2.3.116 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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(+)-camphene synthase (EC 4.2.3.116) is an enzyme with systematic name geranyl-diphosphate diphosphate-lyase (cyclizing, (+)-camphene-forming).[1][2][3][4] This enzyme catalyses the following chemical reaction
Cyclase I of Salvia officinalis (sage) gives about equal parts (+)-camphene and (+)-alpha-pinene.
References
- ^ Gambliel, H.; Croteau, R. (1984). "Pinene cyclases I and II. Two enzymes from sage (Salvia officinalis) which catalyze stereospecific cyclizations of geranyl pyrophosphate to monoterpene olefins of opposite configuration". J. Biol. Chem. 259 (2): 740–748. PMID 6693393.
- ^ Croteau, R.; Satterwhite, D.M.; Cane, D.E.; Chang, C.C. (1988). "Biosynthesis of monoterpenes. Enantioselectivity in the enzymatic cyclization of (+)- and (−)-linalyl pyrophosphate to (+)- and (−)-pinene and (+)- and (−)-camphene". J. Biol. Chem. 263 (21): 10063–10071. PMID 3392006.
- ^ Wagschal, K.C.; Pyun, H.J.; Coates, R.M.; Croteau, R. (1994). "Monoterpene biosynthesis: isotope effects associated with bicyclic olefin formation catalyzed by pinene synthases from sage (Salvia officinalis)". Arch. Biochem. Biophys. 308: 477–487. doi:10.1006/abbi.1994.1068. PMID 8109978.
- ^ Pyun, H.J.; Wagschal, K.C.; Jung, D.I.; Coates, R.M.; Croteau, R. (1994). "Stereochemistry of the proton elimination in the formation of (+)- and (−)-α-pinene by monoterpene cyclases from sage (Salvia officinalis)". Arch. Biochem. Biophys. 308: 488–496. doi:10.1006/abbi.1994.1069. PMID 8109979.
External links
- (+)-camphene+synthase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)