1540s in architecture
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|1530s . 1540s in architecture . 1550s|
- 1545 - Part of the Biblioteca Marciana in Venice collapses, causing the architect, Jacopo Sansovino, to be imprisoned briefly.
- 1546 - Michelangelo Buonarroti is made chief architect of St. Peter's Basilica in Rome.
- 1549 - The spire of Lincoln Cathedral in England is blown down.
- c. 1541
- 1541–1544 - Old Hall of Berkhamsted School in England built
- Andrea Palladio completes his first commission at Villa Godi, first of his Palladian villas of Veneto; the neighbouring Villa Piovene is completed at about the same time
- Church of Saint Lucius, designed by Tommaso Rodari in the style of Bramante, is completed at its original location in Lugano, Switzerland
- Approximate date of completion of more of the Device Forts on the coast of England: Pendennis and St Mawes Castles in Cornwall, East Cowes Castle on the Isle of Wight and Sandsfoot Castle at Weymouth, Dorset
- 1543 - Lighthouse of Genoa completed in present form
- 1544 - King's College Chapel, Cambridge completed
- 1544–1549 - Xuanfu–Datong section of Ming Great Wall of China constructed
- c. 1546 - Loggetta del Sansovino of St Mark's Campanile in Piazza San Marco, Venice, designed by Jacopo Sansovino, is completed
- 1543: June 25 - Giovanni Mangone, Italian sculptor, architect, military engineer and antiquarian