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16-alpha-hydroxyprogesterone dehydratase

From Wikipedia, the free encyclopedia
16α-hydroxyprogesterone dehydratase
Identifiers
EC no.4.2.1.98
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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PMCarticles
PubMedarticles
NCBIproteins

The enzyme 16α-hydroxyprogesterone dehydratase (EC 4.2.1.98) catalyzes the chemical reaction

16α-hydroxyprogesterone = 16,17-didehydroprogesterone + H2O

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is 16α-hydroxyprogesterone hydro-lyase (16,17-didehydroprogesterone-forming). Other names in common use include hydroxyprogesterone dehydroxylase, 16α-hydroxyprogesterone dehydroxylase, 16α-dehydroxylase, and 16α-hydroxyprogesterone hydro-lyase.

References

[edit]
  • Glass TL, Lamppa RS (1985). "Purification and properties of 16 alpha-hydroxyprogesterone dehydroxylase from Eubacterium sp. strain 144". Biochim. Biophys. Acta. 837 (2): 103–10. doi:10.1016/0005-2760(85)90232-2. PMID 4052439.