|Millennium:||1st millennium BC|
|163 BC by topic|
|Gregorian calendar||163 BC
|Ab urbe condita||591|
|Ancient Egypt era||XXXIII dynasty, 161|
|- Pharaoh||Ptolemy VI Philometor, 18|
|Ancient Greek era||154th Olympiad, year 2|
|Chinese calendar||丁丑年 (Fire Ox)
2534 or 2474
— to —
戊寅年 (Earth Tiger)
2535 or 2475
|Coptic calendar||−446 – −445|
|Ethiopian calendar||−170 – −169|
|- Vikram Samvat||−106 – −105|
|- Shaka Samvat||N/A|
|- Kali Yuga||2938–2939|
|Iranian calendar||784 BP – 783 BP|
|Islamic calendar||808 BH – 807 BH|
|Minguo calendar||2074 before ROC
|Seleucid era||149/150 AG|
|Thai solar calendar||380–381|
Year 163 BC was a year of the pre-Julian Roman calendar. At the time it was known as the Year of the Consulship of Gracchus and Thalna (or, less frequently, year 591 Ab urbe condita). The denomination 163 BC for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years.
- The Egyptian king Ptolemy VI Philometor is restored to his throne through the intervention of the citizens of Alexandria. However, the Romans intervene and decide to partition the Ptolemaic realm, ordering Ptolemy VIII Euergetes into Cyrenaica and giving Ptolemy VI Cyprus and Egypt. The two brothers accept the Roman partition.
- In the turmoil following the death of Antiochus IV, the governor of Media, Timarchus becomes the independent ruler of Media, opposing Lysias who is acting as regent for young king Antiochus V Eupator.
- Lysias tries to make peace with the Jews in Judea. He offers them full religious freedom if they will lay down their arms. Even though the Chasidim consent, Judas Maccabeus argues for full political as well as religious freedom.
- The Roman playwright Terence's play Heauton Timorumenos ("The Self-Tormentor") is first performed.
- Tiberius Sempronius Gracchus, Roman politician, who, as a plebeian tribune, will cause political turmoil in the Republic through his attempts to legislate agrarian reforms; his political ideals will eventually lead to his death at the hands of supporters of the conservative faction (Optimates) of the Roman Senate (d. 132 BC)
- Marcus Aemilius Scaurus, Roman politician and ambassador (d. 89 BC)
- Zhang Yan, known formally as Empress Xiaohui, empress of the Chinese Han Dynasty (b. 202 BC)
- Xin Zhui, Chinese noblewoman
- Harrison (2005). A Companion to Latin Literature. Wiley-Blackwell. p. 137.