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3,4-dihydroxyphenylalanine reductive deaminase

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3,4-dihydroxyphenylalanine reductive deaminase
Identifiers
EC no.4.3.1.22
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The enzyme 3,4-dihydroxyphenylalanine reductive deaminase (EC 4.3.1.22, reductive deaminase, DOPA-reductive deaminase, DOPARDA; systematic name 3,4-dihydroxy-L-phenylalanine ammonia-lyase (3,4-dihydroxyphenylpropanoate-forming))[1] catalyses the following chemical reaction

L-dopa + 2 NADH 3,4-dihydroxyphenylpropanoate + 2 NAD+ + NH3

This enzyme participates in L-phenylalanine catabolism in the anaerobic phototrophic bacterium Rhodobacter sphaeroides OU5.

References

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  1. ^ Ranjith NK, Sasikala C, Ramana C (2007). "Catabolism of L-phenylalanine and L-yrosine by Rhodobacter sphaeroides OU5 occurs through 3,4-dihydroxyphenylalanine". Research in Microbiology. 158 (6): 506–11. doi:10.1016/j.resmic.2007.04.008. PMID 17616348.
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