PABPC5
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| PABPC5 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| Aliases | PABPC5, PABP5, poly(A) binding protein cytoplasmic 5 | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 300407; MGI: 2136401; HomoloGene: 5857; GeneCards: PABPC5; OMA:PABPC5 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Poly(A) binding protein cytoplasmic 5 is a protein that in humans is encoded by the PABPC5 gene. [5]
Function
[edit]This gene encodes a poly(A)-binding protein that binds to the polyA tail found at the 3' end of most eukaryotic mRNAs. It is thought to play a role in the regulation of mRNA metabolic processes in the cytoplasm. This gene is located in a gene-poor region within the X-specific 13d-sY43 subinterval of the chromosome Xq21.3/Yp11.2 homology block. It is located close to translocation breakpoints associated with premature ovarian failure, and is therefore a potential candidate gene for this disorder. [provided by RefSeq, May 2010].
References
[edit]- ^ a b c GRCh38: Ensembl release 89: ENSG00000174740 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000034732 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: Poly(A) binding protein cytoplasmic 5". Retrieved 2020-04-16.
Further reading
[edit]
 | This article on a gene on the human X chromosome and/or its associated protein is a stub. You can help Wikipedia by expanding it. |
This article incorporates text from the United States National Library of Medicine, which is in the public domain.