DENND1A

DENND1A
Identifiers
Aliases	DENND1A, FAM31A, KIAA1608, DENN domain containing 1A
External IDs	OMIM: 613633; MGI: 2442794; HomoloGene: 17141; GeneCards: DENND1A; OMA:DENND1A - orthologs
Gene location (Human) Chr. Chromosome 9 (human) Band 9q33.3 Start 123,379,654 bp End 123,930,152 bp
Gene location (Mouse) Chr. Chromosome 2 (mouse) Band 2|2 B Start 37,689,003 bp End 38,177,402 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in monocyte bone marrow cells ventricular zone mucosa of ileum granulocyte right frontal lobe cingulate gyrus anterior cingulate cortex prefrontal cortex blood Top expressed in neural layer of retina zygote primary visual cortex dentate gyrus of hippocampal formation granule cell superior frontal gyrus secondary oocyte muscle of thigh right kidney spermatocyte spermatid More reference expression data BioGPS More reference expression data
Gene ontology Molecular function guanyl-nucleotide exchange factor activity SH3 domain binding lipid binding phosphatidylinositol phosphate binding phosphatidylinositol-3-phosphate binding Cellular component membrane plasma membrane synapse cell junction soma dendrite clathrin-coated vesicle membrane presynaptic membrane cytoplasmic vesicle clathrin-coated vesicle nucleoplasm cytosol intracellular membrane-bounded organelle Biological process endocytosis regulation of Rab protein signal transduction synaptic vesicle endocytosis protein transport positive regulation of GTPase activity endocytic recycling Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 57706 227801 Ensembl ENSG00000119522 ENSMUSG00000035392 UniProt Q8TEH3 Q8K382 RefSeq (mRNA) NM_020946 NM_024820 NM_001352964 NM_001352965 NM_001352966 NM_001352967 NM_001352968 NM_001393654 NM_001400446 NM_001400449 NM_146122 NM_001362973 NM_001362977 NM_001362978 RefSeq (protein) NP_065997 NP_079096 NP_001339893 NP_001339894 NP_001339895 NP_001339896 NP_001339897 NP_666234 NP_001349902 NP_001349906 NP_001349907 Location (UCSC) Chr 9: 123.38 – 123.93 Mb Chr 2: 37.69 – 38.18 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

DENN domain-containing protein 1A is a protein that in humans is encoded by the DENND1A gene.

Further reading

• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9". Nature. 429 (6990): 369–74. Bibcode:2004Natur.429..369H. doi:10.1038/nature02465. PMC 2734081. PMID 15164053.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.