PLXDC1

PLXDC1
Identifiers
Aliases	PLXDC1, TEM3, TEM7, plexin domain containing 1
External IDs	OMIM: 606826; MGI: 1919574; HomoloGene: 10700; GeneCards: PLXDC1; OMA:PLXDC1 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	39,154,394 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	97,877,270 bp
RNA expression pattern
	Top expressed in
	apex of heart; ; tendon of biceps brachii; ; right ovary; ; gallbladder; ; left uterine tube; ; left ovary; ; body of uterus; ; right uterine tube; ; tibial nerve; ; gastric mucosa;
	Top expressed in
	motor neuron; ; facial motor nucleus; ; lateral geniculate nucleus; ; medial geniculate nucleus; ; lobe of cerebellum; ; medial dorsal nucleus; ; seminiferous tubule; ; cerebellar vermis; ; lumbar subsegment of spinal cord; ; spermatid;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	cytoplasm; integral component of membrane; extracellular region; cell junction; soma; receptor complex; plasma membrane; dendrite; intracellular anatomical structure; membrane; bicellular tight junction; extracellular space;
Biological process	angiogenesis; spinal cord development;
	Sources:Amigo / QuickGO
Orthologs
	57125
	72324
	ENSG00000161381
	ENSMUSG00000017417
	Q8IUK5
	Q91ZV7
	NM_020405
	NM_001163608; NM_028199
	NP_065138
	NP_001157080; NP_082475
	Wikidata
View/Edit Human	View/Edit Mouse

Plexin domain-containing protein 1 is a protein that in humans is encoded by the PLXDC1 gene.^[5]^[6]^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000161381 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000017417 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ St Croix B, Rago C, Velculescu V, Traverso G, Romans KE, Montgomery E, Lal A, Riggins GJ, Lengauer C, Vogelstein B, Kinzler KW (Aug 2000). "Genes expressed in human tumor endothelium". Science. 289 (5482): 1197–202. Bibcode:2000Sci...289.1197S. doi:10.1126/science.289.5482.1197. PMID 10947988.
^ Carson-Walter EB, Watkins DN, Nanda A, Vogelstein B, Kinzler KW, St Croix B (Sep 2001). "Cell surface tumor endothelial markers are conserved in mice and humans". Cancer Res. 61 (18): 6649–55. PMID 11559528.
^ "Entrez Gene: PLXDC1 plexin domain containing 1".

Fuchs B, Mahlum E, Halder C, et al. (2007). "High expression of tumor endothelial marker 7 is associated with metastasis and poor survival of patients with osteogenic sarcoma". Gene. 399 (2): 137–43. doi:10.1016/j.gene.2007.05.003. PMC 2066185. PMID 17560052.
Nanda A, Buckhaults P, Seaman S, et al. (2005). "Identification of a binding partner for the endothelial cell surface proteins TEM7 and TEM7R". Cancer Res. 64 (23): 8507–11. doi:10.1158/0008-5472.CAN-04-2716. PMID 15574754.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.

This article on a gene on human chromosome 17 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000161381 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000017417 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10947988-5] St Croix B, Rago C, Velculescu V, Traverso G, Romans KE, Montgomery E, Lal A, Riggins GJ, Lengauer C, Vogelstein B, Kinzler KW (Aug 2000). "Genes expressed in human tumor endothelium". Science. 289 (5482): 1197–202. Bibcode:2000Sci...289.1197S. doi:10.1126/science.289.5482.1197. PMID 10947988.

[pmid11559528-6] Carson-Walter EB, Watkins DN, Nanda A, Vogelstein B, Kinzler KW, St Croix B (Sep 2001). "Cell surface tumor endothelial markers are conserved in mice and humans". Cancer Res. 61 (18): 6649–55. PMID 11559528.

[entrez-7] "Entrez Gene: PLXDC1 plexin domain containing 1".

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References

Further reading