FBRS

FBRS
Identifiers
Aliases	FBRS, FBS, FBS1, fibrosin
External IDs	OMIM: 608601; MGI: 104648; HomoloGene: 79554; GeneCards: FBRS; OMA:FBRS - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	30,670,810 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	127,090,883 bp
RNA expression pattern
	Top expressed in
	left testis; ; right testis; ; right uterine tube; ; anterior pituitary; ; granulocyte; ; right lobe of thyroid gland; ; skin of leg; ; cerebellar vermis; ; left lobe of thyroid gland; ; gastric mucosa;
	Top expressed in
	granulocyte; ; zygote; ; secondary oocyte; ; thymus; ; spleen; ; primary oocyte; ; lip; ; adrenal gland; ; esophagus; ; bone marrow;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	growth factor activity;
Cellular component	extracellular space;
Biological process	positive regulation of fibroblast proliferation; regulation of signaling receptor activity;
	Sources:Amigo / QuickGO
Orthologs
	64319
	14123
	ENSG00000156860
	ENSMUSG00000042423
	Q9HAH7
	Q8R089
	NM_001105079; NM_022452
	NM_010183
	NP_001098549
	NP_034313
	Wikidata
View/Edit Human	View/Edit Mouse

Probable fibrosin-1 long transcript protein is a protein that in humans is encoded by the FBRS gene.^[5]^[6]^[7]

Fibrosin is a lymphokine secreted by activated lymphocytes that induces fibroblast proliferation (Prakash and Robbins, 1998).^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000156860 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000042423 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Prakash S, Robbins PW, Wyler DJ (Apr 1995). "Cloning and analysis of murine cDNA that encodes a fibrogenic lymphokine, fibrosin". Proc Natl Acad Sci U S A. 92 (6): 2154–8. Bibcode:1995PNAS...92.2154P. doi:10.1073/pnas.92.6.2154. PMC 42442. PMID 7892239.
^ Prakash S, Robbins PW (Nov 1998). "Cloning and analysis of the cDNA for human fibrosin, a novel fibrogenic lymphokine". DNA Cell Biol. 17 (10): 879–84. doi:10.1089/dna.1998.17.879. PMID 9809749.
^ ^a ^b "Entrez Gene: FBS1 fibrosin 1".

Hillier LD, Lennon G, Becker M, et al. (1997). "Generation and analysis of 280,000 human expressed sequence tags". Genome Res. 6 (9): 807–28. doi:10.1101/gr.6.9.807. PMID 8889549.
Prakash S, Nanji AA, Robbins PW (1999). "Fibrosin: A novel lymphokine in alcohol-induced fibrosis". Exp. Mol. Pathol. 67 (1): 40–9. doi:10.1006/exmp.1999.2274. PMID 10493891.
Prakash S, Robbins PW (2002). "Fibrosin: a novel lymphokine in wound healing". Exp. Mol. Pathol. 71 (3): 247–55. doi:10.1006/exmp.2001.2402. PMID 11733950.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
Prakash S, Paul WE, Robbins PW (2007). "Fibrosin, a novel fibrogenic cytokine, modulates expression of myofibroblasts". Exp. Mol. Pathol. 82 (1): 42–8. doi:10.1016/j.yexmp.2006.06.008. PMID 17083929.

This article on a gene on human chromosome 16 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000156860 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000042423 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid7892239-5] Prakash S, Robbins PW, Wyler DJ (Apr 1995). "Cloning and analysis of murine cDNA that encodes a fibrogenic lymphokine, fibrosin". Proc Natl Acad Sci U S A. 92 (6): 2154–8. Bibcode:1995PNAS...92.2154P. doi:10.1073/pnas.92.6.2154. PMC 42442. PMID 7892239.

[pmid9809749-6] Prakash S, Robbins PW (Nov 1998). "Cloning and analysis of the cDNA for human fibrosin, a novel fibrogenic lymphokine". DNA Cell Biol. 17 (10): 879–84. doi:10.1089/dna.1998.17.879. PMID 9809749.

[entrez-7] "Entrez Gene: FBS1 fibrosin 1".

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References

Further reading