From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
Protein AF-10 is a protein that in humans is encoded by the MLLT10 gene .[ 5] [ 6]
Interactions
MLLT10 has been shown to interact with SS18 .[ 7]
References
^ a b c GRCh38: Ensembl release 89: ENSG00000078403 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000026743 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Chaplin T, Ayton P, Bernard OA, Saha V, Della Valle V, Hillion J, Gregorini A, Lillington D, Berger R, Young BD (Apr 1995). "A novel class of zinc finger/leucine zipper genes identified from the molecular cloning of the t(10;11) translocation in acute leukemia" . Blood . 85 (6): 1435–41. doi :10.1182/blood.V85.6.1435.bloodjournal8561435 PMID 7888665 . ^ "Entrez Gene: MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10" .^ de Bruijn DR, dos Santos NR, Thijssen J, Balemans M, Debernardi S, Linder B, Young BD, Geurts van Kessel A (May 2001). "The synovial sarcoma associated protein SYT interacts with the acute leukemia associated protein AF10" . Oncogene . 20 (25): 3281–9. doi :10.1038/sj.onc.1204419 PMID 11423977 .
Further reading
Silliman CC, McGavran L, Wei Q, Miller LA, Li S, Hunger SP (1998). "Alternative splicing in wild-type AF10 and CALM cDNAs and in AF10-CALM and CALM-AF10 fusion cDNAs produced by the t(10;11)(p13-14;q14-q21) suggests a potential role for truncated AF10 polypeptides" . Leukemia . 12 (9): 1404–10. doi :10.1038/sj.leu.2401109 PMID 9737689 . Linder B, Newman R, Jones LK, Debernardi S, Young BD, Freemont P, Verrijzer CP, Saha V (2000). "Biochemical analyses of the AF10 protein: the extended LAP/PHD-finger mediates oligomerisation". J. Mol. Biol . 299 (2): 369–78. doi :10.1006/jmbi.2000.3766 . PMID 10860745 . Lillington DM, Jaju RJ, Shankar AG, Neat M, Kearney L, Young BD, Saha V (2000). "Cytogenetic and molecular evidence of marrow involvement in extramedullary acute myeloid leukaemia" . Br. J. Haematol . 110 (3): 547–51. doi :10.1046/j.1365-2141.2000.02212.x PMID 10997963 . S2CID 45898713 . de Bruijn DR, dos Santos NR, Thijssen J, Balemans M, Debernardi S, Linder B, Young BD, Geurts van Kessel A (2001). "The synovial sarcoma associated protein SYT interacts with the acute leukemia associated protein AF10" . Oncogene . 20 (25): 3281–9. doi :10.1038/sj.onc.1204419 PMID 11423977 . Debernardi S, Bassini A, Jones LK, Chaplin T, Linder B, de Bruijn DR, Meese E, Young BD (2002). "The MLL fusion partner AF10 binds GAS41, a protein that interacts with the human SWI/SNF complex" . Blood . 99 (1): 275–81. doi :10.1182/blood.V99.1.275 PMID 11756182 . Cai Y, Gao Y, Sheng Q, Miao S, Cui X, Wang L, Zong S, Koide SS (2002). "Characterization and potential function of a novel testis-specific nucleoporin BS-63". Mol. Reprod. Dev . 61 (1): 126–34. doi :10.1002/mrd.1139 . PMID 11774384 . S2CID 23631919 . Roll P, Zattara-Cannoni H, Bustos-Bernard MC, Curtillet C, Michel G, Vagner-Capodano AM (2002). "Molecular and fluorescence in situ hybridization analysis of a 10;11 rearrangement in a case of infant acute monocytic leukemia". Cancer Genet. Cytogenet . 135 (2): 187–91. doi :10.1016/S0165-4608(01)00644-6 . PMID 12127405 . Nakamura T, Mori T, Tada S, Krajewski W, Rozovskaia T, Wassell R, Dubois G, Mazo A, Croce CM, Canaani E (2002). "ALL-1 is a histone methyltransferase that assembles a supercomplex of proteins involved in transcriptional regulation" . Mol. Cell . 10 (5): 1119–28. doi :10.1016/S1097-2765(02)00740-2 PMID 12453419 . Perrin L, Bloyer S, Ferraz C, Agrawal N, Sinha P, Dura JM (2003). "The leucine zipper motif of the Drosophila AF10 homologue can inhibit PRE-mediated repression: implications for leukemogenic activity of human MLL-AF10 fusions" . Mol. Cell. Biol . 23 (1): 119–30. doi :10.1128/MCB.23.1.119-130.2003 . PMC 140655 PMID 12482966 . Okada Y, Feng Q, Lin Y, Jiang Q, Li Y, Coffield VM, Su L, Xu G, Zhang Y (2005). "hDOT1L links histone methylation to leukemogenesis" . Cell . 121 (2): 167–78. doi :10.1016/j.cell.2005.02.020 PMID 15851025 . S2CID 15638573 .
