Elephantiasis
| Elephantiasis | |
|---|---|
 | |
| Elephantiasis of the legs due to filariasis. | |
| Specialty | Infectious disease, general surgery |
| Symptoms | Swelling of the skin |
Elephantiasis, often incorrectly called elephantitis, is the enlargement and hardening of limbs or body parts due to tissue swelling.[1][2] It is characterised by edema, hypertrophy, and fibrosis of skin and subcutaneous tissues, due to obstruction of lymphatic vessels.[2] It may affect the genitalia.[2] The term elephantiasis is often used in reference to (symptoms caused by) parasitic worm infections,[1][2] but may refer to a variety of diseases that swell parts of the subject's body to exceptionally massive proportions.[2]
Cause
Some conditions that present with elephantiasis include:
- Elephantiasis nostras, due to longstanding chronic lymphangitis[citation needed]
- Elephantiasis tropica (known as lymphatic filariasis), caused by a number of parasitic worms, particularly Wuchereria bancrofti. More than 120 million people, mostly in Africa and Southeast Asia, are affected.[3]
- Nonfilarial elephantiasis (or podoconiosis), an immune disease affecting the lymph vessels[citation needed]
- Leishmaniasis[2]
- Elephantiasis, Grade 3 lymphedema which may occur in people with breast cancer[4]
- Genital elephantiasis, result of lymphogranuloma venereum[citation needed]
- Proteus syndrome, a genetic disorder best known as the condition possibly experienced by Joseph Merrick, the so-called "Elephant Man"[citation needed]
Other causes may include:
- Repeated streptococcal infection[2]
- Lymphadenectomy[2]
- Hereditary birth defects[2]
- Pretibial myxedema
References
- ^ a b "Definition of ELEPHANTIASIS". www.merriam-webster.com. Retrieved 2018-06-28.
- ^ a b c d e f g h i "elephantiasis", The Free Dictionary, retrieved 2018-06-28
- ^ Carlson, Emily (27 March 2013). "Taking the 'Bite' Out of Vector-Borne Diseases - Inside Life Science Series - National Institute of General Medical Sciences". publications.nigms.nih.gov. Retrieved 29 November 2016.
- ^ "Lymphedema". National Cancer Institute. 29 May 2015. Retrieved 29 November 2016.
External links
- . Encyclopædia Britannica. Vol. VIII (9th ed.). 1878. p. 126.
- "Lymphatic filariasis". World Health Organization. Retrieved 1 June 2018.
This article includes a list of related items that share the same name (or similar names).
If an internal link incorrectly led you here, you may wish to change the link to point directly to the intended article.
If an internal link incorrectly led you here, you may wish to change the link to point directly to the intended article.