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List of Schedule III controlled substances (U.S.)

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This is the list of Schedule III controlled substances as defined by the United States Controlled Substances Act at 21 U.S.C. § 812(c) and 21 CFR 1308.13. The following findings are required for substances to be placed in this schedule:[1]

  1. The drug or other substance has a potential for abuse less than the drugs or other substances in schedules I and II.
  2. The drug or other substance has a currently accepted medical use in treatment in the United States.
  3. Abuse of the drug or other substance may lead to moderate or low physical dependence or high psychological dependence.

The complete list of Schedule III substances is as follows. The Administrative Controlled Substances Code Number and Federal Register citation for each substance is included.

Stimulants

ACSCN Drug
1405 See 21 CFR 1308.13(b)(1)
1228 Benzphetamine[2]
1645 Chlorphentermine[2]
1647 Clortermine[2]
1615 Phendimetrazine[2]

Depressants

ACSCN Drug
2100 Any derivative of barbituric acid[3][note 1]
2510 Chlorhexadol[3][note 1]
2020 Embutramide[4]
2012 FDA-approved oxybate products[5]
2261 Perampanel[6]
7285 Ketamine[7]
7300 Lysergic acid[3][note 1]
7310 Lysergic acid amide[3][note 1]
2575 Methyprylon[3][note 1]
2600 Sulfondiethylmethane[3][note 1]
2605 Sulfonethylmethane[3][note 1]
2610 Sulfonmethane[3][note 1]
7295 Tiletamine and zolazepam[8]

Others

ACSCN Drug
9400 Nalorphine[3][note 1]

Narcotics

ACSCN Drug
9803 Not more than 1.8 grams of codeine per 100 milliliters or not more than 90 milligrams per dosage unit, with an equal or greater quantity of an isoquinoline alkaloid of opium[3][note 1]
9804 Not more than 1.8 grams of codeine per 100 milliliters or not more than 90 milligrams per dosage unit, with one or more active, nonnarcotic ingredients in recognized therapeutic amounts[3][note 1]
9807 Not more than 1.8 grams of dihydrocodeine per 100 milliliters or not more than 90 milligrams per dosage unit, with one or more active nonnarcotic ingredients in recognized therapeutic amounts[3][note 1]
9808 Not more than 300 milligrams of ethylmorphine per 100 milliliters or not more than 15 milligrams per dosage unit, with one or more active, nonnarcotic ingredients in recognized therapeutic amounts[3][note 1]
9809 Not more than 500 milligrams of opium per 100 milliliters or per 100 grams or not more than 25 milligrams per dosage unit, with one or more active, nonnarcotic ingredients in recognized therapeutic amounts[3][note 1]
9810 Not more than 50 milligrams of morphine per 100 milliliters or per 100 grams, with one or more active, nonnarcotic ingredients in recognized therapeutic amounts[3][note 1]
9064 Buprenorphine[9]

Steroids

ACSCN Drug
4000 Anabolic steroids

Hallucinogens

ACSCN Drug
7369 Dronabinol in sesame oil and encapsulated in a soft gelatin capsule[10]

Notes

  1. ^ a b c d e f g h i j k l m n o This substance was expressly scheduled by the Controlled Substances Act on October 27, 1970. The 1974 Federal Register ruling (by Administrator John R. Bartels, Jr.) merely organized its listing in the Code of Federal Regulations.

References

  1. ^ 21 U.S.C. § 812(b)(3) retrieved September 3, 2014
  2. ^ a b c d Ingersoll, John (June 15, 1973). "Schedules of Controlled Substances; Placement of Benzphetamine, Chlorphentermine, Clotermine, Diethylpropion, Mazindol, Phendimetrazine, and Phentermine in Schedule III" (PDF). Isomer Design. Bureau of Narcotics and Dangerous Drugs. Archived (PDF) from the original on May 19, 2019. Retrieved January 16, 2023.
  3. ^ a b c d e f g h i j k l m n o Bartels Jr., John R. (June 20, 1974). "PART 1308— SCHEDULES OF CONTROLLED SUBSTANCES: Annual Publication" (PDF). Government Publishing Office. Drug Enforcement Administration. Archived from the original (PDF) on September 6, 2023. Retrieved September 6, 2023.
  4. ^ Leonhart, Michele (August 29, 2006). "Schedules of Controlled Substances: Placement of Embutramide Into Schedule III". Federal Register. Drug Enforcement Administration. Retrieved January 16, 2023.
  5. ^ Marshall, Donnie (March 13, 2000). "Schedules of Controlled Substances: Addition of Gamma-Hydroxybutyric Acid to Schedule I". Federal Register. Drug Enforcement Administration.
  6. ^ Harrigan, Thomas (October 22, 2013). "Department of Justice. Drug Enforcement Administration. Schedules of Controlled Substances: Placement of Perampanel into Schedule III" (PDF). Federal Register. 78 (204). Office of the Federal Register, National Archives and Records Administration: 62500–62506. Retrieved 22 February 2014.
  7. ^ Marshall, Donnie (July 13, 1999). "Schedules of Controlled Substances: Placement of Ketamine into Schedule III". Federal Register. Drug Enforcement Administration. Archived from the original on September 6, 2023. Retrieved September 6, 2023.
  8. ^ Lawn, John (January 21, 1987). "Schedules of Controlled Substances: Placement of Preparations Which Contain Both Tiletamine and Zolazepam into Schedule III" (PDF). Isomer Design. Drug Enforcement Administration. Archived (PDF) from the original on March 3, 2022. Retrieved January 16, 2023.
  9. ^ Brown, John (October 7, 2002). "Schedules of Controlled Substances: Rescheduling of Buprenorphine From Schedule V to Schedule III". Federal Register. Drug Enforcement Administration. Retrieved January 16, 2023.
  10. ^ Marshall, Donnie (July 2, 1999). "Schedules of controlled substances: rescheduling of the Food and Drug Administration approved product containing synthetic dronabinol in sesame oil and encapsulated in soft gelatin capsules from schedule II to schedule III" (PDF). Federal Register. Drug Enforcement Administration. Retrieved January 16, 2023.
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