CD300C

CD300C
Identifiers
Aliases	CD300C, CLM-6, CMRF-35, CMRF-35A, CMRF35, CMRF35-A1, CMRF35A, CMRF35A1, IGSF16, LIR, CD300c molecule
External IDs	OMIM: 606786; MGI: 2153249; HomoloGene: 74580; GeneCards: CD300C; OMA:CD300C - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	74,546,115 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	114,892,706 bp
RNA expression pattern
	Top expressed in
	monocyte; ; granulocyte; ; blood; ; spleen; ; upper lobe of left lung; ; appendix; ; right lung; ; bone marrow; ; right coronary artery; ; Descending thoracic aorta;
	Top expressed in
	stroma of bone marrow; ; granulocyte; ; spleen; ; blood; ; calvaria; ; right lung lobe; ; mesenteric lymph nodes; ; tibiofemoral joint; ; thymus; ; seminal vesicula;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transmembrane signaling receptor activity;
Cellular component	integral component of membrane; plasma membrane; integral component of plasma membrane; membrane;
Biological process	cellular defense response; immune system process; regulation of immune response; signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	10871
	140497
	ENSG00000167850
	ENSMUSG00000044811
	Q08708
	Q7TSN2
	NM_006678
	NM_134158
	NP_006669
	NP_598919
	Wikidata
View/Edit Human	View/Edit Mouse

CMRF35-like molecule 6 (CLM-6) also known as CD300 antigen-like family member C (CD300c) is a protein that in humans is encoded by the CD300C gene.^[5]^[6]^[7]

The CMRF35 antigen, which was identified by reactivity with a monoclonal antibody, is present on monocytes, neutrophils, and some T and B lymphocytes.^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000167850 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000044811 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Jackson DG, Hart DN, Starling G, Bell JI (Jun 1992). "Molecular cloning of a novel member of the immunoglobulin gene superfamily homologous to the polymeric immunoglobulin receptor". Eur J Immunol. 22 (5): 1157–63. doi:10.1002/eji.1830220508. PMID 1349532.
^ Clark GJ, Green BJ, Hart DN (Aug 2000). "The CMRF-35H gene structure predicts for an independently expressed member of an ITIM/ITAM pair of molecules localized to human chromosome 17". Tissue Antigens. 55 (2): 101–9. doi:10.1034/j.1399-0039.2000.550201.x. PMID 10746781.
^ ^a ^b "Entrez Gene: CD300C CD300c molecule".

External links

Human CD300C genome location and CD300C gene details page in the UCSC Genome Browser.

Clark GJ, Fitzpatrick S, Kuo B, Modra C, Jamriska L, Hart DN (2002). "CMRF-35A, CMRF-35H: potential new CD". J. Biol. Regul. Homeost. Agents. 16 (3): 233–5. PMID 12456026.
Cannon JP, Haire RN, Litman GW (December 2002). "Identification of diversified genes that contain immunoglobulin-like variable regions in a protochordate". Nat. Immunol. 3 (12): 1200–7. doi:10.1038/ni849. PMID 12415263.
Clark GJ, Cooper B, Fitzpatrick S, Green BJ, Hart DN (May 2001). "The gene encoding the immunoregulatory signaling molecule CMRF-35A localized to human chromosome 17 in close proximity to other members of the CMRF-35 family". Tissue Antigens. 57 (5): 415–23. doi:10.1034/j.1399-0039.2001.057005415.x. PMID 11556966.

This article on a gene on human chromosome 17 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000167850 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000044811 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1349532-5] Jackson DG, Hart DN, Starling G, Bell JI (Jun 1992). "Molecular cloning of a novel member of the immunoglobulin gene superfamily homologous to the polymeric immunoglobulin receptor". Eur J Immunol. 22 (5): 1157–63. doi:10.1002/eji.1830220508. PMID 1349532.

[pmid10746781-6] Clark GJ, Green BJ, Hart DN (Aug 2000). "The CMRF-35H gene structure predicts for an independently expressed member of an ITIM/ITAM pair of molecules localized to human chromosome 17". Tissue Antigens. 55 (2): 101–9. doi:10.1034/j.1399-0039.2000.550201.x. PMID 10746781.

[entrez-7] "Entrez Gene: CD300C CD300c molecule".

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References

External links

Further reading