AGTPBP1 (gene)

AGTPBP1
Identifiers
Aliases	AGTPBP1, CCP1, NNA1, ATP/GTP binding protein 1, CONDCA, ATP/GTP binding carboxypeptidase 1
External IDs	OMIM: 606830; MGI: 2159437; HomoloGene: 9067; GeneCards: AGTPBP1; OMA:AGTPBP1 - orthologs
Gene location (Human) Chr. Chromosome 9 (human) Band 9q21.33 Start 85,546,539 bp End 85,742,029 bp
Gene location (Mouse) Chr. Chromosome 13 (mouse) Band 13 B2|13 Start 59,593,556 bp End 59,733,041 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in corpus callosum monocyte bone marrow bone marrow cells inferior olivary nucleus trabecular bone right ventricle blood Pars compacta optic nerve Top expressed in spermatid dentate gyrus of hippocampal formation granule cell spermatocyte cerebellar cortex superior frontal gyrus facial motor nucleus lobe of cerebellum cerebellar vermis neural layer of retina primary visual cortex More reference expression data BioGPS n/a
Gene ontology Molecular function carboxypeptidase activity tubulin binding zinc ion binding peptidase activity metallopeptidase activity hydrolase activity metal ion binding metallocarboxypeptidase activity Cellular component cytoplasm cytosol mitochondrion nucleus nucleolus intracellular membrane-bounded organelle Biological process mitochondrion organization olfactory bulb development C-terminal protein deglutamylation neuromuscular process eye photoreceptor cell differentiation protein side chain deglutamylation proteolysis cerebellar Purkinje cell differentiation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 23287 67269 Ensembl ENSG00000135049 ENSMUSG00000021557 UniProt Q9UPW5 Q641K1 RefSeq (mRNA) NM_001286715 NM_001286717 NM_015239 NM_001330701 NM_001048008 NM_001284218 NM_001284219 NM_001284221 NM_023328 NM_001377097 RefSeq (protein) NP_001273644 NP_001273646 NP_001317630 NP_056054 NP_056054.2 NP_001041473 NP_001271147 NP_001271148 NP_001271150 NP_075817 NP_001364026 Location (UCSC) Chr 9: 85.55 – 85.74 Mb Chr 13: 59.59 – 59.73 Mb PubMed search
Wikidata
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ATP/GTP binding protein 1 is a protein that in humans is encoded by the AGTPBP1 gene.

Function

NNA1 is a zinc carboxypeptidase that contains nuclear localization signals and an ATP/GTP-binding motif that was initially cloned from regenerating spinal cord neurons of the mouse.[supplied by OMIM, Jul 2002].

Further reading

• Thakar K, Karaca S, Port SA, Urlaub H, Kehlenbach RH (March 2013). "Identification of CRM1-dependent Nuclear Export Cargos Using Quantitative Mass Spectrometry". Mol. Cell. Proteomics. 12 (3): 664–78. doi:10.1074/mcp.M112.024877. PMC 3591659. PMID 23242554.{{cite journal}}: CS1 maint: unflagged free DOI (link)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.