TCTN3

TCTN3
Identifiers
Aliases	TCTN3, C10orf61, JBTS18, OFD4, TECT3, tectonic family member 3
External IDs	OMIM: 613847; MGI: 1914840; HomoloGene: 9221; GeneCards: TCTN3; OMA:TCTN3 - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	95,694,143 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	40,600,677 bp
RNA expression pattern
	Top expressed in
	corpus epididymis; ; decidua; ; stromal cell of endometrium; ; islet of Langerhans; ; caput epididymis; ; right lobe of thyroid gland; ; pancreatic ductal cell; ; left lobe of thyroid gland; ; gallbladder; ; tail of epididymis;
	Top expressed in
	fourth ventricle; ; choroid plexus of fourth ventricle; ; choroidal fissure; ; spermatocyte; ; saccule; ; otic vesicle; ; spermatid; ; lumbar subsegment of spinal cord; ; islet of Langerhans; ; visual cortex;
	More reference expression data
	n/a
Orthologs
	26123
	67590
	ENSG00000119977
	ENSMUSG00000025008
	Q6NUS6
	Q8R2Q6
	NM_001143973; NM_015631
	NM_026260; NM_001365072
	NP_001137445; NP_056446
	NP_080536; NP_001352001
	Wikidata
View/Edit Human	View/Edit Mouse

Tectonic family member 3 is a protein in humans that is encoded by the TCTN3 gene. ^[5]

This gene encodes a member of the tectonic gene family which functions in Hedgehog signal transduction and development of the neural tube. Mutations in this gene have been associated with Oral-facial-digital syndrome IV and Joubert syndrome 18. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2012].

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000119977 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000025008 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Tectonic family member 3". Retrieved 2012-12-22.

References

Further reading