Oxprenoate potassium

Oxprenoate potassium
Clinical data
Other names	RU-28318; 17α-Hydroxy-3-oxo-7α-propylpregn-4-ene-21-carboxylic acid monopotassium salt
Drug class	Antimineralocorticoid
Identifiers
	IUPAC name potassium 3-[(7R,8R,9S,10R,13S,14S,17R)-17-Hydroxy-10,13-dimethyl-3-oxo-7-propyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]propanoate;
CAS Number	76676-34-1;
PubChem CID	23677972;
ChemSpider	64295;
UNII	167NDD8MTE;
CompTox Dashboard (EPA)	DTXSID401337179 ;
Chemical and physical data
Formula	C25H37KO4
Molar mass	440.665 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCC[C@@H]1CC2=CC(=O)CC[C@@]2([C@@H]3[C@@H]1[C@@H]4CC[C@]([C@]4(CC3)C)(CCC(=O)[O-])O)C.[K+];
	InChI InChI=1S/C25H38O4.K/c1-4-5-16-14-17-15-18(26)6-10-23(17,2)19-7-11-24(3)20(22(16)19)8-12-25(24,29)13-9-21(27)28;/h15-16,19-20,22,29H,4-14H2,1-3H3,(H,27,28);/q;+1/p-1/t16-,19+,20+,22-,23+,24+,25-;/m1./s1; Key:HXJITUGMCJCKCE-UYOQDFFISA-M;

Oxprenoate potassium (developmental code name RU-28318) is a synthetic steroidal antimineralocorticoid which was never marketed.^[1] The affinities of oxprenoate potassium for the steroid hormone receptors have been reported.^[2]

References

^ J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 922–. ISBN 978-1-4757-2085-3.
^ Raynaud JP; Fortin M; Hunt P; Ojasoo T; Doré JC; Surcouf E; Mornon JP (1986). "Approaches to drug development using receptors". In Antonio M. Gotto; Bert W. O'Malley; Fondation Princesse Liliane (eds.). The Role of Receptors in Biology and Medicine: Proceedings of the Ninth Argenteuil Symposium. Raven Press. pp. 65–77. ISBN 978-0-88167-161-2.

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