RPP14

RPP14
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3IR3
Identifiers
Aliases	RPP14, P14, HsHTD2, ribonuclease P/MRP subunit p14
External IDs	OMIM: 606112; MGI: 1914303; HomoloGene: 5113; GeneCards: RPP14; OMA:RPP14 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	58,324,695 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	14,389,406 bp
RNA expression pattern
	Top expressed in
	muscle of thigh; ; gonad; ; gastrocnemius muscle; ; Achilles tendon; ; mucosa of transverse colon; ; stromal cell of endometrium; ; testicle; ; epithelium of colon; ; ventricular zone; ; smooth muscle tissue;
	Top expressed in
	ventricular zone; ; seminal vesicula; ; embryo; ; embryo; ; morula; ; sternocleidomastoid muscle; ; epiblast; ; temporal muscle; ; triceps brachii muscle; ; facial motor nucleus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	ribonuclease activity; hydrolase activity; RNA binding; ribonuclease P activity; lyase activity; 3-hydroxyacyl-CoA dehydratase activity;
Cellular component	nucleus; nucleoplasm; multimeric ribonuclease P complex; nucleolus; mitochondrion; mitochondrial matrix;
Biological process	RNA phosphodiester bond hydrolysis; RNA phosphodiester bond hydrolysis, endonucleolytic; tRNA processing; tRNA 5'-leader removal; fatty acid metabolic process; lipid metabolism; fatty-acyl-CoA biosynthetic process;
	Sources:Amigo / QuickGO
Orthologs
	11102
	67053
	ENSG00000163684
	ENSMUSG00000023156
	O95059; P86397
	Q9CQH8
	NM_001098783; NM_007042
	NM_025938
NP_001092253; NP_008973; NP_001335641; NP_001335642; NP_001335643;
	NP_001335644
	NP_080214
	Wikidata
View/Edit Human	View/Edit Mouse

Ribonuclease P protein subunit p14 is an enzyme that in humans is encoded by the RPP14 gene.^[5]^[6]^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000163684 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000023156 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Jarrous N, Eder PS, Wesolowski D, Altman S (Mar 1999). "Rpp14 and Rpp29, two protein subunits of human ribonuclease P". RNA. 5 (2): 153–157. doi:10.1017/S135583829800185X. PMC 1369747. PMID 10024167.
^ Jiang T, Altman S (Apr 2002). "A protein subunit of human RNase P, Rpp14, and its interacting partner, OIP2, have 3'-->5' exoribonuclease activity". Proc Natl Acad Sci U S A. 99 (8): 5295–5300. doi:10.1073/pnas.072083699. PMC 122763. PMID 11929972.
^ "Entrez Gene: RPP14 ribonuclease P 14kDa subunit".

Jiang T, Altman S (2001). "Protein-protein interactions with subunits of human nuclear RNase P". Proc. Natl. Acad. Sci. U.S.A. 98 (3): 920–925. doi:10.1073/pnas.021561498. PMC 14685. PMID 11158571.
Venter JC; Adams MD; Myers EW; et al. (2001). "The sequence of the human genome". Science. 291 (5507): 1304–1351. doi:10.1126/science.1058040. PMID 11181995. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
Jiang T, Guerrier-Takada C, Altman S (2001). "Protein-RNA interactions in the subunits of human nuclear RNase P". RNA. 7 (7): 937–941. doi:10.1017/S1355838201010299. PMC 1370153. PMID 11455963.
Strausberg RL; Feingold EA; Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
Ota T; Suzuki Y; Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–45. doi:10.1038/ng1285. PMID 14702039. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
Welting TJ, van Venrooij WJ, Pruijn GJ (2004). "Mutual interactions between subunits of the human RNase MRP ribonucleoprotein complex". Nucleic Acids Res. 32 (7): 2138–2146. doi:10.1093/nar/gkh539. PMC 407822. PMID 15096576.
Brandenberger R; Wei H; Zhang S; et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation". Nat. Biotechnol. 22 (6): 707–716. doi:10.1038/nbt971. PMID 15146197. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
Suzuki Y; Yamashita R; Shirota M; et al. (2004). "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions". Genome Res. 14 (9): 1711–1718. doi:10.1101/gr.2435604. PMC 515316. PMID 15342556. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
Gerhard DS; Wagner L; Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–2127. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
Andersen JS; Lam YW; Leung AK; et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. doi:10.1038/nature03207. PMID 15635413. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
Rual JF; Venkatesan K; Hao T; et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–1178. doi:10.1038/nature04209. PMID 16189514. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
Kimura K; Wakamatsu A; Suzuki Y; et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)

This article on a gene on human chromosome 3 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000163684 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000023156 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10024167-5] Jarrous N, Eder PS, Wesolowski D, Altman S (Mar 1999). "Rpp14 and Rpp29, two protein subunits of human ribonuclease P". RNA. 5 (2): 153–157. doi:10.1017/S135583829800185X. PMC 1369747. PMID 10024167.

[pmid11929972-6] Jiang T, Altman S (Apr 2002). "A protein subunit of human RNase P, Rpp14, and its interacting partner, OIP2, have 3'-->5' exoribonuclease activity". Proc Natl Acad Sci U S A. 99 (8): 5295–5300. doi:10.1073/pnas.072083699. PMC 122763. PMID 11929972.

[entrez-7] "Entrez Gene: RPP14 ribonuclease P 14kDa subunit".

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[3]

[4]

[5]

[6]

[7]

References

Further reading