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Layilin

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LAYN
Identifiers
AliasesLAYN, Layilin
External IDsMGI: 2685357; HomoloGene: 18716; GeneCards: LAYN; OMA:LAYN - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001258390
NM_001258391
NM_178834
NM_001318799

NM_001033534

RefSeq (protein)

NP_001245319
NP_001245320
NP_001305728
NP_849156

NP_001028706

Location (UCSC)Chr 11: 111.54 – 111.56 MbChr 9: 50.97 – 50.99 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Layilin is a protein that in humans is encoded by the LAYN gene.[5]

Medical Relevance

A study has shown that Layilin is upregulated in tumor infiltrating CD8+ Cytotoxic T cells of patients with liver cancer.[6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000204381Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000060594Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Layilin".
  6. ^ Zheng C, Zheng L, Yoo JK, Guo H, Zhang Y, Guo X, Kang B, Hu R, Huang JY, Zhang Q, Liu Z, Dong M, Hu X, Ouyang W, Peng J, Zhang Z (2017). "Landscape of Infiltrating T Cells in Liver Cancer Revealed by Single-Cell Sequencing". Cell. 169 (7): 1342–1356.e16. doi:10.1016/j.cell.2017.05.035. PMID 28622514.

Further reading