LIMCH1

LIMCH1
Identifiers
Aliases	LIMCH1, LIMCH1A, LMO7B, LIM and calponin homology domains 1
External IDs	OMIM: 617750; MGI: 1924819; HomoloGene: 18953; GeneCards: LIMCH1; OMA:LIMCH1 - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	41,700,044 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	67,057,158 bp
RNA expression pattern
	Top expressed in
	lower lobe of lung; ; internal globus pallidus; ; inferior ganglion of vagus nerve; ; olfactory bulb; ; corpus callosum; ; dorsal motor nucleus of vagus nerve; ; inferior olivary nucleus; ; subthalamic nucleus; ; superior vestibular nucleus; ; external globus pallidus;
	Top expressed in
	sciatic nerve; ; left lung; ; right lung; ; left lung lobe; ; right lung lobe; ; retinal pigment epithelium; ; epithelium of lens; ; myocardium of ventricle; ; right ventricle; ; ankle;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	actin binding; metal ion binding; myosin II head/neck binding;
Cellular component	stress fiber; myosin II complex; cytoplasm; cytoskeleton;
Biological process	actomyosin structure organization; positive regulation of protein phosphorylation; negative regulation of cell migration; positive regulation of stress fiber assembly; regulation of focal adhesion assembly;
	Sources:Amigo / QuickGO
Orthologs
	22998
	77569
	ENSG00000064042
	ENSMUSG00000037736
	Q9UPQ0
	Q3UH68
NM_001112717; NM_001112718; NM_001112719; NM_001112720; NM_001289122;
	NM_001289124; NM_014988; NM_001330672; NM_001330674; NM_001330784; NM_001330786; NM_001330787; NM_001330788; NM_001330789; NM_001330790; NM_001330791; NM_001330792; NM_001330793; NM_001330982; NM_001330983
	NM_001001980; NM_001256122; NM_001368863
NP_001106188; NP_001106189; NP_001106190; NP_001106191; NP_001276051;
	NP_001276053; NP_001317601; NP_001317603; NP_001317713; NP_001317715; NP_001317716; NP_001317717; NP_001317718; NP_001317719; NP_001317720; NP_001317721; NP_001317722; NP_001317911; NP_001317912; NP_055803
NP_001001980; NP_001243051; NP_001355792; NP_001388339; NP_001388340;
	NP_001388341; NP_001388342; NP_001388343; NP_001388344; NP_001388345; NP_001388346; NP_001388347; NP_001388348; NP_001388349; NP_001388350; NP_001388351; NP_001388352; NP_001388353; NP_001388354; NP_001388355; NP_001388356; NP_001390437; NP_001390438
	Wikidata
View/Edit Human	View/Edit Mouse

LIM and calponin homology domains-containing protein 1 is a protein that in humans is encoded by the LIMCH1 gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000064042 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000037736 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Kikuno R, Nagase T, Ishikawa K, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Oct 1999). "Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 6 (3): 197–205. doi:10.1093/dnares/6.3.197. PMID 10470851.
^ "Entrez Gene: DKFZP686A01247 hypothetical protein".

"Toward a complete human genome sequence". Genome Res. 8 (11): 1097–108. 1999. doi:10.1101/gr.8.11.1097. PMID 9847074.
Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.

This article on a gene on human chromosome 4 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000064042 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000037736 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10470851-5] Kikuno R, Nagase T, Ishikawa K, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Oct 1999). "Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 6 (3): 197–205. doi:10.1093/dnares/6.3.197. PMID 10470851.

[entrez-6] "Entrez Gene: DKFZP686A01247 hypothetical protein".

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References

Further reading