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ELL (gene)

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ELL
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesELL, C19orf17, ELL1, MEN, PPP1R68, elongation factor for RNA polymerase II
External IDsOMIM: 600284; MGI: 109377; HomoloGene: 4762; GeneCards: ELL; OMA:ELL - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_006532

NM_007924

RefSeq (protein)

NP_006523

NP_031950

Location (UCSC)Chr 19: 18.44 – 18.52 MbChr 8: 70.99 – 71.05 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

RNA polymerase II elongation factor ELL is an enzyme that in humans is encoded by the ELL gene.[5][6][7]

Interactions

ELL (gene) has been shown to interact with P53.[8]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000105656Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000070002Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Thirman MJ, Levitan DA, Kobayashi H, Simon MC, Rowley JD (Jan 1995). "Cloning of ELL, a gene that fuses to MLL in a t(11;19)(q23;p13.1) in acute myeloid leukemia". Proc Natl Acad Sci U S A. 91 (25): 12110–4. doi:10.1073/pnas.91.25.12110. PMC 45386. PMID 7991593.
  6. ^ Shilatifard A, Lane WS, Jackson KW, Conaway RC, Conaway JW (Apr 1996). "An RNA polymerase II elongation factor encoded by the human ELL gene". Science. 271 (5257): 1873–6. doi:10.1126/science.271.5257.1873. PMID 8596958.
  7. ^ "Entrez Gene: ELL elongation factor RNA polymerase II".
  8. ^ Shinobu N, Maeda T, Aso T, Ito T, Kondo T, Koike K, Hatakeyama M (Jun 1999). "Physical interaction and functional antagonism between the RNA polymerase II elongation factor ELL and p53". J. Biol. Chem. 274 (24): 17003–10. doi:10.1074/jbc.274.24.17003. PMID 10358050.

Further reading