ELL (gene)

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Elongation factor RNA polymerase II
Protein ELL PDB 2doa.png
PDB rendering based on 2doa.
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols ELL ; C19orf17; ELL1; MEN; PPP1R68
External IDs OMIM600284 MGI109377 HomoloGene4762 GeneCards: ELL Gene
RNA expression pattern
PBB GE ELL 204096 s at tn.png
PBB GE ELL 204095 s at tn.png
PBB GE ELL gnf1h09335 s at tn.png
More reference expression data
Species Human Mouse
Entrez 8178 13716
Ensembl ENSG00000105656 ENSMUSG00000070002
UniProt P55199 O08856
RefSeq (mRNA) NM_006532 NM_007924
RefSeq (protein) NP_006523 NP_031950
Location (UCSC) Chr 19:
18.44 – 18.52 Mb
Chr 8:
70.54 – 70.59 Mb
PubMed search [1] [2]

RNA polymerase II elongation factor ELL is an enzyme that in humans is encoded by the ELL gene.[1][2][3]


ELL (gene) has been shown to interact with P53.[4]


  1. ^ Thirman MJ, Levitan DA, Kobayashi H, Simon MC, Rowley JD (Jan 1995). "Cloning of ELL, a gene that fuses to MLL in a t(11;19)(q23;p13.1) in acute myeloid leukemia". Proc Natl Acad Sci U S A 91 (25): 12110–4. doi:10.1073/pnas.91.25.12110. PMC 45386. PMID 7991593. 
  2. ^ Shilatifard A, Lane WS, Jackson KW, Conaway RC, Conaway JW (Apr 1996). "An RNA polymerase II elongation factor encoded by the human ELL gene". Science 271 (5257): 1873–6. doi:10.1126/science.271.5257.1873. PMID 8596958. 
  3. ^ "Entrez Gene: ELL elongation factor RNA polymerase II". 
  4. ^ Shinobu N, Maeda T, Aso T, Ito T, Kondo T, Koike K, Hatakeyama M (Jun 1999). "Physical interaction and functional antagonism between the RNA polymerase II elongation factor ELL and p53". J. Biol. Chem. 274 (24): 17003–10. doi:10.1074/jbc.274.24.17003. PMID 10358050. 

Further reading[edit]