RCL1

RCL1
Identifiers
Aliases	RCL1, RNAC, RPCL1, RNA terminal phosphate cyclase like 1
External IDs	OMIM: 611405; MGI: 1913275; HomoloGene: 4217; GeneCards: RCL1; OMA:RCL1 - orthologs
Gene location (Human) Chr. Chromosome 9 (human) Band 9p24.1 Start 4,792,944 bp End 4,885,917 bp
Gene location (Mouse) Chr. Chromosome 19 (mouse) Band 19|19 C1 Start 29,078,775 bp End 29,121,329 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in buccal mucosa cell right lobe of liver tendon of biceps brachii Achilles tendon tibial arteries body of pancreas cartilage tissue skin of leg skin of abdomen left coronary artery Top expressed in left lobe of liver embryo embryo epiblast somite morula morula primitive streak yolk sac fetal liver hematopoietic progenitor cell More reference expression data BioGPS n/a
Gene ontology Molecular function catalytic activity RNA-3'-phosphate cyclase activity endoribonuclease activity Cellular component nucleus nucleoplasm nucleolus Biological process RNA processing ribosome biogenesis endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) rRNA processing endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) biological process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10171 59028 Ensembl ENSG00000120158 ENSMUSG00000024785 UniProt Q9Y2P8 Q9JJT0 RefSeq (mRNA) NM_001286699 NM_001286700 NM_001286701 NM_005772 NM_021525 RefSeq (protein) NP_001273628 NP_001273629 NP_001273630 NP_005763 NP_067500 Location (UCSC) Chr 9: 4.79 – 4.89 Mb Chr 19: 29.08 – 29.12 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

RNA 3'-terminal phosphate cyclase-like protein is an enzyme that in humans is encoded by the RCL1 gene.

See also

• Fibrillarin
• Small nucleolar RNA U3
• RRP9
• UTP6
• UTP11L
• UTP14A
• UTP15

Further reading

• Kimura K; Wakamatsu A; Suzuki Y; et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
• Andersen JS; Lam YW; Leung AK; et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. doi:10.1038/nature03207. PMID 15635413. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
• Gerhard DS; Wagner L; Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–2127. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
• Humphray SJ; Oliver K; Hunt AR; et al. (2004). "DNA sequence and analysis of human chromosome 9". Nature. 429 (6990): 369–374. doi:10.1038/nature02465. PMC 2734081. PMID 15164053. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
• Ota T; Suzuki Y; Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–45. doi:10.1038/ng1285. PMID 14702039. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
• Strausberg RL; Feingold EA; Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
• Andersen JS; Lyon CE; Fox AH; et al. (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. doi:10.1016/S0960-9822(01)00650-9. PMID 11790298. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
• Zhang QH; Ye M; Wu XY; et al. (2001). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells". Genome Res. 10 (10): 1546–1560. doi:10.1101/gr.140200. PMC 310934. PMID 11042152. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
• Billy E, Wegierski T, Nasr F, Filipowicz W (2000). "Rcl1p, the yeast protein similar to the RNA 3'-phosphate cyclase, associates with U3 snoRNP and is required for 18S rRNA biogenesis". EMBO J. 19 (9): 2115–2126. doi:10.1093/emboj/19.9.2115. PMC 305690. PMID 10790377.
• Suzuki Y; Yoshitomo-Nakagawa K; Maruyama K; et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–156. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
• Genschik P, Billy E, Swianiewicz M, Filipowicz W (1997). "The human RNA 3'-terminal phosphate cyclase is a member of a new family of proteins conserved in Eucarya, Bacteria and Archaea". EMBO J. 16 (10): 2955–2967. doi:10.1093/emboj/16.10.2955. PMC 1169903. PMID 9184239.
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–174. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Vicente O, Filipowicz W (1988). "Purification of RNA 3'-terminal phosphate cyclase from HeLa cells. Covalent modification of the enzyme with different nucleotides". Eur. J. Biochem. 176 (2): 431–439. doi:10.1111/j.1432-1033.1988.tb14300.x. PMID 3416880.

External links

• RCL1 human gene location in the UCSC Genome Browser.
• RCL1 human gene details in the UCSC Genome Browser.