European Sleep Apnea Database
Formation | 2006 |
---|---|
Type | Collaborative database |
Legal status | Active |
Purpose | Compile information about sleep apnea |
Fields | Medicine, Internal medicine, Sleep medicine, Sleep apnea |
Key people | Jan Hedner |
Affiliations | European Cooperation in Science and Technology Sahlgrenska Academy at Gothenburg University |
Website | Official website |
The European Sleep Apnea Database (ESADA) (also referred to with spelling European Sleep Apnoea Database[1][2] and European Sleep Apnoea Cohort[3][4]) is a collaboration between European sleep centres as part of the European Cooperation in Science and Technology (COST) Action B 26. The main contractor of the project is the Sahlgrenska Academy at Gothenburg University, Institute of Medicine, Department of Internal Medicine, and the co-ordinator is Jan Hedner, MD, PhD, Professor of Sleep Medicine.[2]
The book Clinical Genomics: Practical Applications for Adult Patient Care said ESADA was an example initiatives which afford an "excellent opportunity" for future collaborative research into genetic aspects of obstructive sleep apnea syndrome (OSAS).[1] Both the European Respiratory Society and the European Sleep Research Society have noted the impact for research cooperative efforts of the database resource.[5]
History
2006 – 2010
In 2006 the European Sleep Apnea Database (ESADA) began as an initiative between 27 European sleep study facilities to combine information and compile it into one shared resource.[5][6] It was formed as part of the European Cooperation in Science and Technology (COST) Action B 26.[2][7] In addition to financial help from COST, the initiative received assistance from companies Philips Respironics and ResMed.[8] The database storing the association's resource information is located in Gothenburg, Sweden.[8] The group's goal was twofold: to serve as a reference guide to those researching sleep disorders, and to compile information about how different caregivers treat patients suffering from sleep apnea.[2][7]
5,103 patients were tracked from March 2007 to August 2009.[7] Data collected on these patients included symptoms suffered, medication, medical history, and sleep data, all inputted into an online format for further analysis.[7] Database researchers reported on their methodology and results in 2010 to the American Thoracic Society, on their observed findings regarding percentages of metabolic and cardiovascular changes related to patients with obstructive sleep apnea.[9] The 2010 research resulted from collaboration between 22 study centres across 16 countries in Europe involving 27 researchers.[9] The primary participants who presented to the American Thoracic Society included researchers from: Sahlgrenska University Hospital, Gothenburg, Sweden; Technion – Israel Institute of Technology, Haifa, Israel; National TB & Lung Diseases Research Institute, Warsaw, Poland; CNR Institute of Biomedicine and Molecular, Palermo, Italy; Instituto Auxologico Italiano, Ospedale San Luca, Milan, Italy; and St. Vincent University Hospital, Dublin, Ireland.[9] Their analysis was published in 2010 in the American Journal of Respiratory and Critical Care Medicine.[9]
2011 – present
In 2011 there were 22 sleep disorder centres in Europe involved in the collaboration.[2][7] The group published research in 2011 analyzing the percentage of patients suffering from sleep apnea that have obesity.[7] By 2012 the database maintained information on over 12,500 patients in Europe; it also contained DNA samples of 2,600 individuals.[8] ESADA was represented in 2012 at the 21st annual meeting of the European Sleep Research Society in Paris, France, and was one of four European Sleep Research Networks that held a session at the event.[10] Pierre Escourrou and Fadia Jilwan wrote a 2012 article for the European Respiratory Journal after studying data from ESADA involving 8,228 total patients from 23 different facilities.[11] They analyzed whether polysomnography was a good measure for hypopnea and sleep apnea.[11] Researchers from the department of pulmonary diseases at Turku University Hospital in Turku, Finland compared variations between sleep centres in the ESADA database and published their findings in the European Respiratory Journal.[12] They looked at the traits of 5,103 patients from 22 centres.[12] They reported on the average age of patients in the database, and the prevalence by region of performing sleep study with cardiorespiratory polygraphy.[12]
The database added a centre in Hamburg, Germany in 2013 managed by physician Holger Hein.[6] The group's annual meeting in 2013 was held in Edinburgh, United Kingdom and was run by Renata Riha.[6] By March 2013, there were approximately 13,000 total patients being studied in the program, with about 200 additional patients being added into the database each month.[5] Analysis published by researchers from Italy and Sweden in September 2013 in the European Respiratory Journal analyzed if there was a correlation between renal function problems and obstructive sleep apnea.[13] They analyzed data from 17 countries in Europe representing 24 sleep centres and 8,112 total patients.[13] They tested whether patients of different types of demographics with other existing health problems had a change in probability of kidney function problems, if they concurrently suffered from obstructive sleep apnea.[13]
In 2014, researchers released data studying 5,294 patients from the database compared prevalence of sleep apnea with increased blood sugar.[14] Their results were published in the European Respiratory Journal.[3][4] They studied glycated hemoglobin levels in the patients and compared them with measured severity in sleep apnea.[15] The researchers analyzed glycated hemoglobin levels among a class of individuals with less severe sleep apnea and those with a higher determined amount of sleep apnea problems.[14] As of 20 March 2014 the database included information on a total of 15,956 patients.[6] A 2014 article in the European Respiratory Journal drawing from the ESADA analyzed whether lack of adequate oxygen during a night's sleep was an indicator for high blood pressure.[16]
Reception
In the 2013 book Clinical Genomics: Practical Applications for Adult Patient Care, ESADA is said to be an example of the kind of initiative which affords an "excellent opportunity" for future collaborative research into genetic aspects of obstructive sleep apnea syndrome (OSAS).[1] Both the European Respiratory Society and the European Sleep Research Society have noted the impact for research cooperative efforts of the database resource.[5]
See also
- Catathrenia
- Deviated septum
- Narcolepsy
- Obesity hypoventilation syndrome
- Congenital central hypoventilation syndrome
- Sleep medicine
- Sleep sex
- Snoring
Notes
- ^ a b c Murray 2013, p. 586.
- ^ a b c d e Hedner 2011, pp. 635–642.
- ^ a b Right Vision News 2014
- ^ a b Daily The Pak Banker 2014
- ^ a b c d ESRS Newsletter 2013
- ^ a b c d Grote 2014
- ^ a b c d e f Obesity, Fitness & Wellness Week 2011, p. 3.
- ^ a b c Grote May 2012, pp. 10–11.
- ^ a b c d Hedner 2010
- ^ ESRS Newsletter 2012, p. 8.
- ^ a b Escourrou 2012
- ^ a b c Saaresranta 2012
- ^ a b c Marrone 2013
- ^ a b Healthcare Purchasing News 2014, p. 16.
- ^ The Huffington Post 2014
- ^ Tkacova 2014, pp. 931–941
References
- "Sleep apnoea could lead to elevated blood sugar levels". Daily The Pak Banker. Islamabad. 5 April 2014 – via LexisNexis.
- Escourrou, Pierre; Fadia Jilwan (1 September 2012). "The method for diagnosis matters in sleep apnea. A systematic analysis of polygraphy and polysomnography data in the European Sleep Apnea Database (ESADA)". European Respiratory Journal. 40 (Suppl 56 184). European Respiratory Society. ISSN 0903-1936. Archived from the original on 23 October 2014. Retrieved 23 October 2014.
- "ESRS 2012 Meeting in Paris" (PDF). ESRS Newsletter. European Sleep Research Society. October 2012. Archived from the original (PDF) on 22 October 2014. Retrieved 22 October 2014.
- "Sleep Apnea Network / European Sleep Apnea Database (ESADA) – A Brief Summary". ESRS Newsletter. European Sleep Research Society. March 2013. Archived from the original on 29 November 2013. Retrieved 21 October 2014.
- "Sleep apnea linked with blood sugar levels". Healthcare Purchasing News. 38 (5): 16. May 2014 – via InfoTrac.
- Hedner, Jan; Ludger Grote; Peretz Lavie; Pawel Sliwinski; Marisa Bonsignore; Gianfranco Parati; Walter T. McNicholas (2010). "The European Sleep Apnea Database (ESADA) – Design And First Interim Crossectional Description Of Results From 22 European Sleep Laboratories". American Journal of Respiratory and Critical Care Medicine. 181. American Thoracic Society: A6857. doi:10.1164/ajrccm-conference.2010.181.1_MeetingAbstracts.A6857. Retrieved 23 October 2014.
- Hedner, Jan (26 May 2011). "The European Sleep Apnoea Database (ESADA): report from 22 European sleep laboratories". European Respiratory Journal. 38 (3). European Respiratory Society: 635–642. doi:10.1183/09031936.00046710. ISSN 0903-1936. PMID 21622583.
- Grote, Ludger (May 2012). "Sleep Apnea Network / European Sleep Apnea Database (ESADA) – An Update" (PDF). ESRS Newsletter. European Sleep Research Society. pp. 10–11. Archived from the original (PDF) on 21 October 2014. Retrieved 21 October 2014.
- Grote, Ludger (March 2014). "The European Sleep Apnea Database (ESADA) – a progress report for the ESRS newsletter". ESRS Newsletter. European Sleep Research Society. Archived from the original on 21 October 2014. Retrieved 21 October 2014.
- "New Study Links Blood Sugar Levels With Sleep Apnea". The Huffington Post. 7 April 2014. Archived from the original on 21 October 2014. Retrieved 21 October 2014.
- Marrone, Oreste; Salvatore Battaglia; Maria Rosaria Bonsignore (1 September 2013). "Relationship between mild to moderate renal dysfunction and obstructive sleep apnea: Data from the European sleep apnea database". European Respiratory Journal. 42 (Suppl 57 P4037). European Respiratory Society. ISSN 0903-1936. Archived from the original on 23 October 2014. Retrieved 23 October 2014.
- Murray, Michael; Monica Giovanni; Mark W. Babyatsky (2013). Clinical Genomics: Practical Applications for Adult Patient Care. McGraw-Hill Professional. p. 586. ISBN 978-0071622448.
- "Data from J. Hedner et al Provide New Insights into Cardiovascular Research". Obesity, Fitness & Wellness Week. NewsRX LLC: 3. 8 October 2011. ISSN 1531-6386 – via InfoTrac.
- "Pakistan: Sleep apnoea could lead to elevated blood sugar levels". Right Vision News. Islamabad. 6 April 2014 – via LexisNexis.
- Tkacova, Ruzena; Walter T. McNichola; Martin Javorsky; Ingo Fietze; Pawel Sliwinski; Gianfranco Parati; Ludger Grote; Jan Hedner (1 October 2014). "Nocturnal intermittent hypoxia predicts prevalent hypertension in the European Sleep Apnoea Database cohort study". European Respiratory Journal. 44 (4). European Respiratory Society: 931–941. doi:10.1183/09031936.00225113. ISSN 0903-1936.
- Saaresranta, Tarja; Marisa Bonsignore; Ludger Grote; Jan Hedner; Walter McNicholas; Josep Montserrat; Thomas Penzel; Martin Pretl; Renata Riha; Pawel Sliwinski; Jan Zielinski (1 September 2012). "Regional differences in characteristics of patients referred to European sleep centers. Results from the European Sleep Apnea Database (ESADA)". European Respiratory Journal. 40 (Suppl 56 4316). European Respiratory Society. ISSN 0903-1936. Retrieved 23 October 2014.
Further reading
- "ESADA – European Sleep Apnea Database". Elicit. Elicit.se. 2014. Archived from the original on 18 October 2014. Retrieved 21 October 2014.
- "Sleep Apnea Diagnostic and Therapeutic Devices Market Expected to Reach USD 6.43 Billion Globally in 2019: Transparency Market Research". India Pharma News. Contify.com. 12 May 2014 – via LexisNexis.