From Wikipedia, the free encyclopedia
Transportin-2 is a protein that in humans is encoded by the TNPO2 gene .[ 5] [ 6] [ 7]
Interactions
TNPO2 has been shown to interact with NXF1 ,[ 6] NUP98 [ 8] Ran (biology) .[ 6]
References
^ a b c GRCh38: Ensembl release 89: ENSG00000105576 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000031691 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Siomi MC, Eder PS, Kataoka N, Wan L, Liu Q, Dreyfuss G (September 1997). "Transportin-mediated nuclear import of heterogeneous nuclear RNP proteins" . The Journal of Cell Biology . 138 (6): 1181–92. doi :10.1083/jcb.138.6.1181 . PMC 2132560 PMID 9298975 . ^ a b c Shamsher MK, Ploski J, Radu A (October 2002). "Karyopherin beta 2B participates in mRNA export from the nucleus" . Proceedings of the National Academy of Sciences of the United States of America . 99 (22): 14195–9. Bibcode :2002PNAS...9914195S . doi :10.1073/pnas.212518199 . PMC 137860 PMID 12384575 . ^ "Entrez Gene: TNPO2 transportin 2 (importin 3, karyopherin beta 2b)" .^ Fontoura BM, Blobel G, Yaseen NR (October 2000). "The nucleoporin Nup98 is a site for GDP/GTP exchange on ran and termination of karyopherin beta 2-mediated nuclear import" . The Journal of Biological Chemistry . 275 (40): 31289–96. doi :10.1074/jbc.M004651200 PMID 10875935 .
Further reading
Gallouzi IE, Steitz JA (November 2001). "Delineation of mRNA export pathways by the use of cell-permeable peptides". Science . 294 (5548): 1895–901. Bibcode :2001Sci...294.1895G . doi :10.1126/science.1064693 . PMID 11729309 . S2CID 43726887 . Blanc V, Kennedy S, Davidson NO (October 2003). "A novel nuclear localization signal in the auxiliary domain of apobec-1 complementation factor regulates nucleocytoplasmic import and shuttling" . The Journal of Biological Chemistry . 278 (42): 41198–204. doi :10.1074/jbc.M302951200 PMID 12896982 . Güttinger S, Mühlhäusser P, Koller-Eichhorn R, Brennecke J, Kutay U (March 2004). "Transportin2 functions as importin and mediates nuclear import of HuR" . Proceedings of the National Academy of Sciences of the United States of America . 101 (9): 2918–23. Bibcode :2004PNAS..101.2918G . doi :10.1073/pnas.0400342101 . PMC 365720 PMID 14981248 . Rebane A, Aab A, Steitz JA (April 2004). "Transportins 1 and 2 are redundant nuclear import factors for hnRNP A1 and HuR" . RNA . 10 (4): 590–9. doi :10.1261/rna.5224304 . PMC 1370549 PMID 15037768 . Lee BJ, Cansizoglu AE, Süel KE, Louis TH, Zhang Z, Chook YM (August 2006). "Rules for nuclear localization sequence recognition by karyopherin beta 2" . Cell . 126 (3): 543–58. doi :10.1016/j.cell.2006.05.049 . PMC 3442361 PMID 16901787 . Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry" . Molecular Systems Biology . 3 (1): 89. doi :10.1038/msb4100134 . PMC 1847948 PMID 17353931 .
