OSGEP

OSGEP
Identifiers
Aliases	OSGEP, Osgep, 1500019L24Rik, GCPL-1, PRSMG1, GCPL1, KAE1, OSGEP1, O-sialoglycoprotein endopeptidase, TCS3, GAMOS3
External IDs	OMIM: 610107; MGI: 1913496; HomoloGene: 6395; GeneCards: OSGEP; OMA:OSGEP - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	20,455,089 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	51,162,350 bp
RNA expression pattern
	Top expressed in
	right hemisphere of cerebellum; ; anterior pituitary; ; right lobe of thyroid gland; ; granulocyte; ; left lobe of thyroid gland; ; right uterine tube; ; right ovary; ; left ovary; ; right frontal lobe; ; canal of the cervix;
	Top expressed in
	interventricular septum; ; ventricular zone; ; neural layer of retina; ; muscle of thigh; ; maxillary prominence; ; mandibular prominence; ; neural tube; ; endocardial cushion; ; somite; ; epiblast;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; acyltransferase activity; metal ion binding; N(6)-L-threonylcarbamoyladenine synthase activity; protein binding; acyltransferase activity, transferring groups other than amino-acyl groups;
Cellular component	nucleoplasm; plasma membrane; nuclear speck; nucleus; EKC/KEOPS complex; cytoplasm;
Biological process	tRNA processing; tRNA threonylcarbamoyladenosine modification;
	Sources:Amigo / QuickGO
Orthologs
	55644
	66246
	ENSG00000092094
	ENSMUSG00000006289
	Q9NPF4
	Q8BWU5
	NM_017807
	NM_133676
	NP_060277
	NP_598437
	Wikidata
View/Edit Human	View/Edit Mouse

Probable O-sialoglycoprotein endopeptidase is an enzyme that in humans is encoded by the OSGEP gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000092094 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000006289 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Seki Y, Ikeda S, Kiyohara H, Ayabe H, Seki T, Matsui H (May 2002). "Sequencing analysis of a putative human O-sialoglycoprotein endopeptidase gene (OSGEP) and analysis of a bidirectional promoter between the OSGEP and APEX genes". Gene. 285 (1–2): 101–8. doi:10.1016/S0378-1119(02)00429-8. PMID 12039036.
^ "Entrez Gene: OSGEP O-sialoglycoprotein endopeptidase".

Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
Vickers JD, Packham MA, Kinlough-Rathbone RL (1997). "Differences between platelet phosphoinositide metabolism stimulated by thrombin or SFLLRN are not accounted for by interaction of thrombin with glycoprotein Ib". Am. J. Hematol. 54 (4): 288–95. doi:10.1002/(SICI)1096-8652(199704)54:4<288::AID-AJH5>3.0.CO;2-R. PMID 9092683.
Yu W, Andersson B, Worley KC, et al. (1997). "Large-Scale Concatenation cDNA Sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
Chervenak JL, Illsley NP (2000). "Episialin acts as an antiadhesive factor in an in vitro model of human endometrial-blastocyst attachment". Biol. Reprod. 63 (1): 294–300. doi:10.1095/biolreprod63.1.294. PMID 10859271.
Kinoshita M, Nakamura T, Ihara M, et al. (2001). "Identification of human endomucin-1 and -2 as membrane-bound O-sialoglycoproteins with anti-adhesive activity". FEBS Lett. 499 (1–2): 121–6. doi:10.1016/S0014-5793(01)02520-0. PMID 11418125.
Armerding D, Fuhlbrigge RC, Kieffer JD, Kupper TS (2001). "Tonsillar B cells do not express PSGL-1, but a significant fraction displays the cutaneous lymphocyte antigen and exhibits effective E- and P-selectin ligand activity". Int. Arch. Allergy Immunol. 126 (1): 78–90. doi:10.1159/000049497. PMID 11641609.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein–protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.

This article on a gene on human chromosome 14 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000092094 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000006289 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12039036-5] Seki Y, Ikeda S, Kiyohara H, Ayabe H, Seki T, Matsui H (May 2002). "Sequencing analysis of a putative human O-sialoglycoprotein endopeptidase gene (OSGEP) and analysis of a bidirectional promoter between the OSGEP and APEX genes". Gene. 285 (1–2): 101–8. doi:10.1016/S0378-1119(02)00429-8. PMID 12039036.

[entrez-6] "Entrez Gene: OSGEP O-sialoglycoprotein endopeptidase".

[1]

[2]

[3]

[4]

[5]

[6]

References

Further reading