Revision as of 21:05, 17 December 2020 by Monkbot(talk | contribs)(Task 18 (cosmetic): eval 10 templates: del empty params (2×); hyphenate params (2×);)
H2A histone family, member B3 is a protein that in humans is encoded by the H2AFB3 gene.[5]
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a member of the histone H2A family. This gene is part of a region that is repeated three times on chromosome X, once in intron 22 of the F8 gene and twice closer to the Xq telomere. This record represents the most telomeric copy. [provided by RefSeq, Jul 2008].[5]
Deng L, de la Fuente C, Fu P, Wang L, Donnelly R, Wade JD, Lambert P, Li H, Lee CG, Kashanchi F (November 2000). "Acetylation of HIV-1 Tat by CBP/P300 increases transcription of integrated HIV-1 genome and enhances binding to core histones". Virology. 277 (2): 278–95. doi:10.1006/viro.2000.0593. PMID11080476.
Deng L, Wang D, de la Fuente C, Wang L, Li H, Lee CG, Donnelly R, Wade JD, Lambert P, Kashanchi F (October 2001). "Enhancement of the p300 HAT activity by HIV-1 Tat on chromatin DNA". Virology. 289 (2): 312–26. doi:10.1006/viro.2001.1129. PMID11689053.
Naylor JA, Buck D, Green P, Williamson H, Bentley D, Giannelli F (July 1995). "Investigation of the factor VIII intron 22 repeated region (int22h) and the associated inversion junctions". Human Molecular Genetics. 4 (7): 1217–24. doi:10.1093/hmg/4.7.1217. PMID8528212.
