From Wikipedia, the free encyclopedia
Schlafen family member 5 is a protein that in humans is encoded by the SLFN5 gene .
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References
Further reading
Katsoulidis E, Mavrommatis E, Woodard J, Shields MA, Sassano A, Carayol N, Sawicki KT, Munshi HG, Platanias LC (December 2010). "Role of interferon {alpha} (IFN{alpha})-inducible Schlafen-5 in regulation of anchorage-independent growth and invasion of malignant melanoma cells" . J. Biol. Chem . 285 (51): 40333–41. doi :10.1074/jbc.M110.151076 . PMC 3001013 . PMID 20956525 . {{cite journal }}
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Sassano A, Mavrommatis E, Arslan AD, Kroczynska B, Beauchamp EM, Khuon S, Chew TL, Green KJ, Munshi HG, Verma AK, Platanias LC (August 2015). "Human Schlafen 5 (SLFN5) Is a Regulator of Motility and Invasiveness of Renal Cell Carcinoma Cells" . Mol. Cell. Biol . 35 (15): 2684–98. doi :10.1128/MCB.00019-15 . PMC 4524119 . PMID 26012550 .
Companioni Nápoles O, Tsao AC, Sanz-Anquela JM, Sala N, Bonet C, Pardo ML, Ding L, Simo O, Saqui-Salces M, Blanco VP, Gonzalez CA, Merchant JL (January 2017). "SCHLAFEN 5 expression correlates with intestinal metaplasia that progresses to gastric cancer" . J. Gastroenterol . 52 (1): 39–49. doi :10.1007/s00535-016-1202-4 . PMC 5045746 . PMID 27032393 .
Arslan AD, Sassano A, Saleiro D, Lisowski P, Kosciuczuk EM, Fischietti M, Eckerdt F, Fish EN, Platanias LC (October 2017). "Human SLFN5 is a transcriptional co-repressor of STAT1-mediated interferon responses and promotes the malignant phenotype in glioblastoma" . Oncogene . 36 (43): 6006–6019. doi :10.1038/onc.2017.205 . PMC 5821504 . PMID 28671669 .