AAMP (gene)

AAMP
Identifiers
Aliases	AAMP, angio associated migratory cell protein
External IDs	OMIM: 603488; MGI: 107809; HomoloGene: 846; GeneCards: AAMP; OMA:AAMP - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	218,270,178 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	74,323,897 bp
RNA expression pattern
	Top expressed in
	body of stomach; ; anterior pituitary; ; gastric mucosa; ; stromal cell of endometrium; ; left lobe of thyroid gland; ; skin of abdomen; ; canal of the cervix; ; gallbladder; ; body of pancreas; ; left uterine tube;
	Top expressed in
	spermatid; ; saccule; ; spermatocyte; ; otic placode; ; seminiferous tubule; ; yolk sac; ; lip; ; entorhinal cortex; ; pyloric antrum; ; molar;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	unfolded protein binding; heparin binding;
Cellular component	microtubule cytoskeleton; intercellular bridge; cytosol; cell surface; plasma membrane; membrane; preribosome, large subunit precursor; cytoplasm;
Biological process	positive regulation of endothelial cell migration; multicellular organism development; cell differentiation; angiogenesis; smooth muscle cell migration; ribosomal large subunit biogenesis;
	Sources:Amigo / QuickGO
Orthologs
	14
	227290
	ENSG00000127837
	ENSMUSG00000006299
	Q13685
	n/a
	NM_001302545; NM_001087
	NM_001190444; NM_146110
	NP_001078; NP_001289474
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Angio-associated, migratory cell protein, also known as AAMP, is a protein which in humans is encoded by the AAMP gene.^[5]

Function

The gene product is an immunoglobulin-type protein. It is found to be expressed strongly in endothelial cells, cytotrophoblasts, and poorly differentiated colon adenocarcinoma cells found in lymphatics.

The protein contains a WD40 domain and a heparin-binding domain which mediates heparin-sensitive cell adhesion.^[5]

Human AAMP genome location and AAMP gene details page in the UCSC Genome Browser.