AC3 or AC-3 may refer to:
Science and technology
- Dolby AC-3, Dolby Digital audio codec
- AC-3 algorithm (Arc Consistency Algorithm 3), one of a series of algorithms used for the solution of constraint satisfaction problems
- (35414) 1998 AC3, a minor planet
- AC-3, an IEC utilization category
- Comte AC-3, a 1920s Swiss bomber/transport aircraft
- Southern Pacific class AC-3, a class of steam locomotive
- Ace Combat 3, part of the Ace Combat series of video games
- Armored Core 3, part of the Armored Core series of video games
- Assassin's Creed III, part of the Assassin's Creed series of video games
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