ADCK3

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COQ8A
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCOQ8A, ARCA2, CABC1, COQ10D4, COQ8, SCAR9, ADCK3, aarF domain containing kinase 3, coenzyme Q8A
External IDsMGI: 1914676 HomoloGene: 11345 GeneCards: COQ8A
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for COQ8A
Genomic location for COQ8A
Band1q42.13Start226,897,536 bp[1]
End226,987,545 bp[1]
RNA expression pattern
PBB GE CABC1 218168 s at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_020247

NM_001163290
NM_023341
NM_001359268
NM_001359269

RefSeq (protein)

NP_064632

NP_001156762
NP_075830
NP_001346197
NP_001346198

Location (UCSC)Chr 1: 226.9 – 226.99 MbChr 1: 180.17 – 180.2 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

aarF domain containing kinase 3 is a protein that in humans is encoded by the ADCK3 gene.[5]

This gene encodes a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. It is not related to the family of ABC transporter proteins. Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage, and inhibiting its expression partially suppresses p53-induced apoptosis. Alternatively spliced transcript variants have been found; however, their full-length nature has not been determined.[5]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000163050 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000026489 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ a b "Entrez Gene: ADCK3 aarF domain containing kinase 3".

External links[edit]

Further reading[edit]