ADCK3

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COQ8A
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases COQ8A, ARCA2, CABC1, COQ10D4, COQ8, SCAR9, ADCK3, aarF domain containing kinase 3, coenzyme Q8A
External IDs MGI: 1914676 HomoloGene: 11345 GeneCards: COQ8A
RNA expression pattern
PBB GE CABC1 218168 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_020247

NM_001163290
NM_023341

RefSeq (protein)

NP_064632

NP_001156762
NP_075830

Location (UCSC) Chr 1: 226.9 – 226.99 Mb Chr 1: 180.17 – 180.2 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

aarF domain containing kinase 3 is a protein that in humans is encoded by the ADCK3 gene.[3]

This gene encodes a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. It is not related to the family of ABC transporter proteins. Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage, and inhibiting its expression partially suppresses p53-induced apoptosis. Alternatively spliced transcript variants have been found; however, their full-length nature has not been determined.[3]

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