Annexin A7

ANXA7
Identifiers
Aliases	ANXA7, ANX7, SNX, SYNEXIN, annexin A7
External IDs	OMIM: 186360; MGI: 88031; HomoloGene: 36149; GeneCards: ANXA7; OMA:ANXA7 - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	73,414,076 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	20,530,201 bp
RNA expression pattern
	Top expressed in
	oocyte; ; islet of Langerhans; ; secondary oocyte; ; beta cell; ; tendon; ; tail of epididymis; ; Achilles tendon; ; gastrocnemius muscle; ; right coronary artery; ; mucosa of paranasal sinus;
	Top expressed in
	skin of external ear; ; lacrimal gland; ; stroma of bone marrow; ; endothelial cell of lymphatic vessel; ; epithelium of stomach; ; primary oocyte; ; esophagus; ; mucous cell of stomach; ; lip; ; ankle;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	calcium ion binding; calcium-dependent protein binding; integrin binding; protein binding; calcium-dependent phospholipid binding; RNA binding; identical protein binding;
Cellular component	vesicle; cytosol; nuclear envelope; endoplasmic reticulum membrane; membrane; plasma membrane; chromaffin granule membrane; extracellular exosome; nucleus; collagen-containing extracellular matrix;
Biological process	hemostasis; epithelial cell differentiation; response to organic cyclic compound; response to salt stress; cellular calcium ion homeostasis; membrane fusion; negative regulation of gene expression; autophagy; response to calcium ion; regulation of cell shape; social behavior; cellular water homeostasis; cell population proliferation;
	Sources:Amigo / QuickGO
Orthologs
	310
	11750
	ENSG00000138279
	ENSMUSG00000021814
	P20073
	Q07076
	NM_001156; NM_004034; NM_001320879; NM_001320880
	NM_001110794; NM_009674; NM_001374757
	NP_001147; NP_001307808; NP_001307809; NP_004025
	NP_001104264; NP_033804; NP_001361686
	Wikidata
View/Edit Human	View/Edit Mouse

Annexin A7 is a protein that in humans is encoded by the ANXA7 gene.^[5]^[6]

Template:PBB Summary

Interactions

ANXA7 has been shown to interact with ALG2^[7] and SRI.^[8]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000138279 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000021814 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Shirvan A, Srivastava M, Wang MG, Cultraro C, Magendzo K, McBride OW, Pollard HB, Burns AL (Jul 1994). "Divergent structure of the human synexin (annexin VII) gene and assignment to chromosome 10". Biochemistry. 33 (22): 6888–901. doi:10.1021/bi00188a019. PMID 7515686.
^ "Entrez Gene: ANXA7 annexin A7".
^ Satoh, Hirokazu; Nakano Yoshimi; Shibata Hideki; Maki Masatoshi (Nov 2002). "The penta-EF-hand domain of ALG-2 interacts with amino-terminal domains of both annexin VII and annexin XI in a Ca2+-dependent manner". Biochim. Biophys. Acta. 1600 (1–2). Netherlands: 61–7. doi:10.1016/S1570-9639(02)00445-4. ISSN 0006-3002. PMID 12445460. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysource=, and |laysummary= (help)
^ Brownawell, A M; Creutz C E (Aug 1997). "Calcium-dependent binding of sorcin to the N-terminal domain of synexin (annexin VII)". J. Biol. Chem. 272 (35). UNITED STATES: 22182–90. doi:10.1074/jbc.272.35.22182. ISSN 0021-9258. PMID 9268363. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysummary=, and |laysource= (help)CS1 maint: unflagged free DOI (link)

Interactions

References

Further reading