AP3S1

AP3S1
Identifiers
Aliases	AP3S1, CLAPS3, Sigma3A, adaptor related protein complex 3 sigma 1 subunit, adaptor related protein complex 3 subunit sigma 1
External IDs	OMIM: 601507; MGI: 1337062; HomoloGene: 4254; GeneCards: AP3S1; OMA:AP3S1 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	115,914,081 bp
Gene location (Mouse)
Chr.	Chromosome 18 (mouse)
End	46,923,893 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; hippocampus proper; ; superior frontal gyrus; ; anterior cingulate cortex; ; amygdala; ; dorsolateral prefrontal cortex; ; nucleus accumbens; ; ascending aorta; ; right coronary artery; ; tibial arteries;
	Top expressed in
	ganglionic eminence; ; thymus; ; white adipose tissue; ; granulocyte; ; neural tube; ; ileum; ; mesencephalon; ; ventricular zone; ; jejunum; ; ovary;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; transporter activity;
Cellular component	AP-3 adaptor complex; membrane coat; Golgi apparatus; AP-type membrane coat adaptor complex; transport vesicle; cytoplasmic vesicle membrane; intracellular membrane-bounded organelle; membrane; cytoplasmic vesicle; axon cytoplasm;
Biological process	anterograde axonal transport; protein transport; insulin receptor signaling pathway; anterograde synaptic vesicle transport; intracellular protein transport; vesicle-mediated transport;
	Sources:Amigo / QuickGO
Orthologs
	1176
	11777
	ENSG00000177879
	ENSMUSG00000024480
	Q92572
	Q9DCR2
NM_001002924; NM_001284; NM_001318090; NM_001318091; NM_001318093;
	NM_001318094
	NM_009681; NM_001303015
NP_001002924; NP_001275; NP_001305019; NP_001305020; NP_001305022;
	NP_001305023; NP_001351048; NP_001351049; NP_001351051
	NP_001289944; NP_033811
	Wikidata
View/Edit Human	View/Edit Mouse

AP-3 complex subunit sigma-1 is a protein that in humans is encoded by the AP3S1 gene.^[5]^[6]^[7] Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000177879 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000024480 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Watanabe TK, Shimizu F, Nagata M, Takaichi A, Fujiwara T, Nakamura Y, Takahashi E, Hirai Y (Sep 1996). "Cloning, expression pattern and mapping to 12p 13.2 --> p13.1 of CLAPS3, a gene encoding a novel clathrin-adaptor small chain". Cytogenet Cell Genet. 73 (3): 214–7. doi:10.1159/000134341. PMID 8697810.
^ Dell'Angelica EC, Ohno H, Ooi CE, Rabinovich E, Roche KW, Bonifacino JS (Apr 1997). "AP-3: an adaptor-like protein complex with ubiquitous expression". EMBO J. 16 (5): 917–28. doi:10.1093/emboj/16.5.917. PMC 1169692. PMID 9118953.
^ "Entrez Gene: AP3S1 adaptor-related protein complex 3, sigma 1 subunit".

References

Further reading