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Actin related protein 2/3 complex, subunit 3, 21kDa
Protein ARPC3 PDB 1k8k.png
PDB rendering based on 1k8k.
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols ARPC3 ; ARC21; p21-Arc
External IDs OMIM604225 MGI1928375 HomoloGene4178 GeneCards: ARPC3 Gene
RNA expression pattern
PBB GE ARPC3 208736 at tn.png
More reference expression data
Species Human Mouse
Entrez 10094 56378
Ensembl ENSG00000111229 ENSMUSG00000029465
UniProt O15145 Q9JM76
RefSeq (mRNA) NM_001278556 NM_019824
RefSeq (protein) NP_001265485 NP_062798
Location (UCSC) Chr 12:
110.43 – 110.45 Mb
Chr 5:
122.39 – 122.41 Mb
PubMed search [1] [2]
ARP2/3 complex ARPC3 (21 kDa) subunit
PDB 1u2v EBI.jpg
crystal structure of arp2/3 complex with bound adp and calcium
Symbol P21-Arc
Pfam PF04062
InterPro IPR007204

Actin-related protein 2/3 complex subunit 3 is a protein that in humans is encoded by the ARPC3 gene.[1][2][3]

This gene encodes one of seven subunits of the Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p21 subunit, has yet to be determined.[3]


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