ASH2L

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ASH2L
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases ASH2L, ASH2, ASH2L1, ASH2L2, Bre2, ASH2 like histone lysine methyltransferase complex subunit
External IDs MGI: 1344416 HomoloGene: 3436 GeneCards: 9070
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001105214
NM_001261832
NM_001282272
NM_004674

NM_001080793
NM_001286207
NM_011791

RefSeq (protein)

NP_001098684.1
NP_001248761.1
NP_004665.2

NP_035921.2

Location (UCSC) Chr 8: 38.11 – 38.14 Mb Chr 8: 25.82 – 25.85 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Set1/Ash2 histone methyltransferase complex subunit ASH2 is an enzyme that in humans is encoded by the ASH2L gene.[1][2]

Interactions[edit]

ASH2L has been shown to interact with MLL.[3]

References[edit]

  1. ^ Ikegawa S, Isomura M, Koshizuka Y, Nakamura Y (Jul 1999). "Cloning and characterization of ASH2L and Ash2l, human and mouse homologs of the Drosophila ash2 gene". Cytogenet. Cell Genet. 84 (3-4): 167–72. doi:10.1159/000015248. PMID 10393421. 
  2. ^ "Entrez Gene: ASH2L ash2 (absent, small, or homeotic)-like (Drosophila)". 
  3. ^ Yokoyama A, Wang Z, Wysocka J, Sanyal M, Aufiero DJ, Kitabayashi I, Herr W, Cleary ML (Jul 2004). "Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression". Mol. Cell. Biol. 24 (13): 5639–49. doi:10.1128/MCB.24.13.5639-5649.2004. PMC 480881. PMID 15199122. 

Further reading[edit]