ATPase ASNA1

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ASNA1
Identifiers
AliasesASNA1, ARSA-I, ARSA1, ASNA-I, GET3, TRC40, hASNA-I, arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
External IDsMGI: 1928379 HomoloGene: 31513 GeneCards: ASNA1
Gene location (Human)
Chromosome 19 (human)
Chr.Chromosome 19 (human)[1]
Chromosome 19 (human)
Genomic location for ASNA1
Genomic location for ASNA1
Band19p13.13Start12,737,139 bp[1]
End12,748,323 bp[1]
RNA expression pattern
PBB GE ASNA1 202024 at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004317

NM_019652
NM_001357202
NM_001357203

RefSeq (protein)

NP_004308

NP_062626
NP_001344131
NP_001344132

Location (UCSC)Chr 19: 12.74 – 12.75 MbChr 8: 85.02 – 85.03 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

ATPase ASNA1 also known as arsenical pump-driving ATPase and arsenite-stimulated ATPase is an enzyme that in humans is encoded by the ASNA1 gene.[5][6]

Function[edit]

ASNA1 is the human homolog of the bacterial arsA gene. In E. coli, arsA ATPase is the catalytic component of a multisubunit oxyanion pump that is responsible for resistance to arsenicals and antimonials.[6]

Interactions[edit]

ASNA1 is found to interact with FAM71D according to STRING [7]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000198356 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000052456 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ Kurdi-Haidar B, Aebi S, Heath D, Enns RE, Naredi P, Hom DK, Howell SB (Feb 1997). "Isolation of the ATP-binding human homolog of the arsA component of the bacterial arsenite transporter". Genomics. 36 (3): 486–91. doi:10.1006/geno.1996.0494. PMID 8884272.
  6. ^ a b "Entrez Gene: ASNA1 arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)".
  7. ^ "STRING 10".

External links[edit]

Further reading[edit]