ATP5J2

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ATP5J2
Identifiers
Aliases ATP5J2, ATP5JL, ATP synthase, H+ transporting, mitochondrial Fo complex subunit F2
External IDs MGI: 1927558 HomoloGene: 3594 GeneCards: ATP5J2
RNA expression pattern
PBB GE ATP5J2 202961 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_020582

RefSeq (protein)

NP_001003713
NP_001003714
NP_001034267
NP_004880

NP_065607.1
NP_065607

Location (UCSC) Chr 7: 99.45 – 99.47 Mb Chr 5: 145.18 – 145.19 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

The ATP5J2 gene [3][4] encodes the ATP synthase subunit f, mitochondrial enzyme in humans.

Function[edit]

Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, F0, which comprises the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and single representatives of the gamma, delta, and epsilon subunits. The proton channel likely has nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the f subunit of the F0 complex. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.[4]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Mao M, Fu G, Wu JS, Zhang QH, Zhou J, Kan LX, Huang QH, He KL, Gu BW, Han ZG, Shen Y, Gu J, Yu YP, Xu SH, Wang YX, Chen SJ, Chen Z (Jul 1998). "Identification of genes expressed in human CD34(+) hematopoietic stem/progenitor cells by expressed sequence tags and efficient full-length cDNA cloning". Proceedings of the National Academy of Sciences of the United States of America. 95 (14): 8175–80. doi:10.1073/pnas.95.14.8175. PMC 20949Freely accessible. PMID 9653160. 
  4. ^ a b "Entrez Gene: ATP5J2 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F2". 

External links[edit]

Further reading[edit]