Acetic formic anhydride
Appearance
Names | |
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Preferred IUPAC name
Acetic formic anhydride | |
Other names
Acetyloxymethanone[citation needed]
Formyl acetate[1] Formic acetic anhydride, ethanoic methanoic anhydride | |
Identifiers | |
3D model (JSmol)
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ChemSpider | |
PubChem CID
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CompTox Dashboard (EPA)
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Properties | |
C3H4O3 | |
Molar mass | 88.062 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Acetic formic anhydride is an organic compound with the chemical formula C
3H
4O
3 and a structural formula of H
3C-(C=O)-O-(C=O)H. It can be viewed as the mixed anhydride of acetic acid and formic acid.
Preparation
Acetic formic anhydride can be produced by reacting sodium formate with acetyl chloride in anhydrous diethyl ether between 23–27 °C.[2]
Applications
Acetic formic anhydride is a formylation agent for amines, amino acids, and alcohols. It is also a starting material for other compounds such as formyl fluoride.[2]
An example of Acetic formic anhydride being used was in the synthesis of Quazodine (U.S. patent 3,248,292).
See also
References
- ^ "Formyl acetate - PubChem Public Chemical Database". The PubChem Project. USA: National Center for Biotechnology Information.
- ^ a b Krimen, Lewis I. (1970). "Acetic Formic Anhydride". Organic Syntheses. 50: 1. doi:10.15227/orgsyn.050.0001.