Adp-ribosyltransferase 5

ART5
Identifiers
Aliases	ART5, ARTC5, ADP-ribosyltransferase 5
External IDs	OMIM: 610625; MGI: 107948; HomoloGene: 7231; GeneCards: ART5; OMA:ART5 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	3,642,316 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	101,758,696 bp
RNA expression pattern
	Top expressed in
	left testis; ; testicle; ; right testis; ; gonad; ; muscle of thigh; ; gastrocnemius muscle; ; left ovary; ; right ovary; ; apex of heart; ; ectocervix;
	Top expressed in
	spermatid; ; spermatocyte; ; muscle of thigh; ; masseter muscle; ; soleus muscle; ; seminiferous tubule; ; plantaris muscle; ; temporal muscle; ; extensor digitorum longus muscle; ; extraocular muscle;
	More reference expression data
	n/a
Gene ontology
Molecular function	NAD+ ADP-ribosyltransferase activity; NAD+ nucleosidase activity; NAD+-protein-arginine ADP-ribosyltransferase activity; transferase activity; glycosyltransferase activity;
Cellular component	extracellular region; membrane;
Biological process	protein ADP-ribosylation; peptidyl-arginine ADP-ribosylation;
	Sources:Amigo / QuickGO
Orthologs
	116969
	11875
	ENSG00000167311
	ENSMUSG00000070424
	Q96L15
	P70352
	NM_001079536; NM_001297668; NM_053017
	NM_001291354; NM_007491
	NP_001073004; NP_001284597; NP_443750
	NP_001278283; NP_031517
	Wikidata
View/Edit Human	View/Edit Mouse

ADP-ribosyltransferase 5 is a protein that in humans is encoded by the ART5 gene. ^[5]

Function

The protein encoded by this gene belongs to the ARG -specific ADP - ribosyltransferase family. Proteins in this family regulate the function of target proteins by attaching ADP -ribose to specific amino acid residues in their target proteins. The mouse homolog lacks a glycosylphosphatidylinositol-anchor signal sequence and is predicted to be a secretory enzyme. Several transcripts encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014].

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000167311 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000070424 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: ADP-ribosyltransferase 5". Retrieved 2018-07-04.

Function

References

Further reading