Afamin

From Wikipedia, the free encyclopedia
Jump to: navigation, search
AFM
Identifiers
Aliases AFM, ALB2, ALBA, ALF, afamin
External IDs MGI: 2429409 HomoloGene: 881 GeneCards: 173
RNA expression pattern
PBB GE AFM 206840 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001133

NM_145146

RefSeq (protein)

NP_001124.1

NP_660128.2

Location (UCSC) Chr 4: 73.48 – 73.5 Mb Chr 5: 90.52 – 90.55 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Afamin is a protein that in humans is encoded by the AFM gene.[1][2]

Function[edit]

This gene is a member of the albumin gene family, which comprises four genes that localize to chromosome 4 in a tandem arrangement. These four genes encode structurally related serum transport proteins that are known to be evolutionarily related. The protein encoded by this gene is regulated developmentally, expressed in the liver and secreted into the bloodstream.[2]

References[edit]

  1. ^ Lichenstein HS, Lyons DE, Wurfel MM, Johnson DA, McGinley MD, Leidli JC, Trollinger DB, Mayer JP, Wright SD, Zukowski MM (Aug 1994). "Afamin is a new member of the albumin, alpha-fetoprotein, and vitamin D-binding protein gene family". J Biol Chem 269 (27): 18149–54. PMID 7517938. 
  2. ^ a b "Entrez Gene: AFM afamin". 

Further reading[edit]