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Symbols AFM ; ALB2; ALBA; ALF
External IDs OMIM104145 MGI2429409 HomoloGene881 GeneCards: AFM Gene
RNA expression pattern
PBB GE AFM 206840 at tn.png
More reference expression data
Species Human Mouse
Entrez 173 280662
Ensembl ENSG00000079557 ENSMUSG00000029369
UniProt P43652 O89020
RefSeq (mRNA) NM_001133 NM_145146
RefSeq (protein) NP_001124 NP_660128
Location (UCSC) Chr 4:
73.48 – 73.5 Mb
Chr 5:
90.52 – 90.55 Mb
PubMed search [1] [2]

Afamin is a protein that in humans is encoded by the AFM gene.[1][2]


This gene is a member of the albumin gene family, which comprises four genes that localize to chromosome 4 in a tandem arrangement. These four genes encode structurally related serum transport proteins that are known to be evolutionarily related. The protein encoded by this gene is regulated developmentally, expressed in the liver and secreted into the bloodstream.[2]


  1. ^ Lichenstein HS, Lyons DE, Wurfel MM, Johnson DA, McGinley MD, Leidli JC, Trollinger DB, Mayer JP, Wright SD, Zukowski MM (Aug 1994). "Afamin is a new member of the albumin, alpha-fetoprotein, and vitamin D-binding protein gene family". J Biol Chem 269 (27): 18149–54. PMID 7517938. 
  2. ^ a b "Entrez Gene: AFM afamin". 

Further reading[edit]