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Alpha-isocomene synthase

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Alpha-isocomene synthase
Identifiers
EC no.4.2.3.136
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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PMCarticles
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NCBIproteins

Alpha-isocomene synthase (EC 4.2.3.136, MrTPS2) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, (-)-alpha-isocomene-forming).[1] This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate (-)-alpha-isocomene + diphosphate

This enzyme is isolated from the roots of the plant Matricaria chamomilla var. recutita (chamomile).

References

  1. ^ Irmisch, S.; Krause, S.T.; Kunert, G.; Gershenzon, J.; Degenhardt, J.; Kollner, T.G. (2012). "The organ-specific expression of terpene synthase genes contributes to the terpene hydrocarbon composition of chamomile essential oils". BMC Plant Biol. 12: #84-84. doi:10.1186/1471-2229-12-84. PMID 22682202.{{cite journal}}: CS1 maint: unflagged free DOI (link)